Endolymphatic hydrops revealed by intravenous gadolinium injection in patients with Ménière's disease

Tsutomu Nakashima, Shinji Naganawa, Masaaki Teranishi, Mitsuhiko Tagaya, Seiichi Nakata, Michihiko Sone, Hironao Otake, Ken Kato, Tomoyuki Iwata, Naoki Nishio

Research output: Contribution to journalArticlepeer-review

79 Citations (Scopus)

Abstract

Conclusion: Visualization of endolymphatic hydrops became possible after intravenous gadolinium (Gd) injection in patients with Ménière's disease. Objective: To visualize endolymphatic hydrops after intravenous Gd injection. Methods: Gd (gadoteridol; 0.2 mmol/kg) was injected intravenously in three patients with unilateral Ménière's disease. We performed three-dimensional fluid attenuated inversion recovery (3D-FLAIR) and three-dimensional real inversion recovery (3D-real IR) magnetic resonance imaging (MRI) 4 h after the injection using a 3-Tesla MRI unit. We used a 32-channel array coil to obtain a high signal-to-noise ratio. Results: Endolymphatic hydrops was observed in the ears of patients with Ménière's disease. However, Gd concentration in the perilymph was lower compared with that obtained after intratympanic Gd injection.

Original languageEnglish
Pages (from-to)338-343
Number of pages6
JournalActa Oto-Laryngologica
Volume130
Issue number3
DOIs
Publication statusPublished - 2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

Fingerprint

Dive into the research topics of 'Endolymphatic hydrops revealed by intravenous gadolinium injection in patients with Ménière's disease'. Together they form a unique fingerprint.

Cite this