Endomyocardial radial strain rate imaging during dobutamine stress echocardiography for the evaluation of contractile reserve in patients with dilated cardiomyopathy

Makoto Minoshima, Akiko Noda, Masakazu Kobayashi, Seiko Miyata, Akihiro Hirashiki, Takahiro Okumura, Hideo Izawa, Hideki Ishii, Takahisa Kondo, Toyoaki Murohara

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

METHODS: Simultaneous echocardiography and left ventricular (LV) catheterization during dobutamine stress were performed in 20 patients with DCM, and echocardiography was performed in 31 control subjects. Dobutamine was infused at a starting dose of 5 μg/kg/min for 5 minutes and then at 10 μg/kg/min. Peak endomyocardial radial strain (ɛ) and systolic strain rate (SRsys ) measured with echocardiography and the maximum first derivative of LV pressure (LV dP/dtmax ) derived from catheterization were used as indices of contractility. Their percentage change from baseline to the dose of 10 μg/kg/min was calculated.

RESULTS: The ɛ and SRsys were significantly smaller in DCM patients than in controls. The LV dP/dtmax , ɛ, and SRsys were significantly higher at the dose of 10 μg/kg/min than at baseline. The percentage change in SRsys was significantly correlated with the percentage change in LV dP/dtmax .

CONCLUSIONS: Strain rate imaging during dobutamine stress in DCM might prove noninvasively informative for the evaluation of myocardial contractile reserve and provide insight into LV systolic dysfunction.

PURPOSE: Myocardial contractile reserve is associated with clinical prognosis in patients with dilated cardiomyopathy (DCM). We assessed myocardial contractile reserve using tissue Doppler strain rate imaging with dobutamine stress echocardiography in DCM patients.

Original languageEnglish
Pages (from-to)555-560
Number of pages6
JournalJournal of clinical ultrasound : JCU
Volume44
Issue number9
DOIs
Publication statusPublished - 12-11-2016

Fingerprint

Stress Echocardiography
Dilated Cardiomyopathy
Dobutamine
Echocardiography
Catheterization
Left Ventricular Dysfunction
Ventricular Pressure

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Minoshima, Makoto ; Noda, Akiko ; Kobayashi, Masakazu ; Miyata, Seiko ; Hirashiki, Akihiro ; Okumura, Takahiro ; Izawa, Hideo ; Ishii, Hideki ; Kondo, Takahisa ; Murohara, Toyoaki. / Endomyocardial radial strain rate imaging during dobutamine stress echocardiography for the evaluation of contractile reserve in patients with dilated cardiomyopathy. In: Journal of clinical ultrasound : JCU. 2016 ; Vol. 44, No. 9. pp. 555-560.
@article{962901f8ae174fe7960bb4be0649c01f,
title = "Endomyocardial radial strain rate imaging during dobutamine stress echocardiography for the evaluation of contractile reserve in patients with dilated cardiomyopathy",
abstract = "METHODS: Simultaneous echocardiography and left ventricular (LV) catheterization during dobutamine stress were performed in 20 patients with DCM, and echocardiography was performed in 31 control subjects. Dobutamine was infused at a starting dose of 5 μg/kg/min for 5 minutes and then at 10 μg/kg/min. Peak endomyocardial radial strain (ɛ) and systolic strain rate (SRsys ) measured with echocardiography and the maximum first derivative of LV pressure (LV dP/dtmax ) derived from catheterization were used as indices of contractility. Their percentage change from baseline to the dose of 10 μg/kg/min was calculated.RESULTS: The ɛ and SRsys were significantly smaller in DCM patients than in controls. The LV dP/dtmax , ɛ, and SRsys were significantly higher at the dose of 10 μg/kg/min than at baseline. The percentage change in SRsys was significantly correlated with the percentage change in LV dP/dtmax .CONCLUSIONS: Strain rate imaging during dobutamine stress in DCM might prove noninvasively informative for the evaluation of myocardial contractile reserve and provide insight into LV systolic dysfunction.PURPOSE: Myocardial contractile reserve is associated with clinical prognosis in patients with dilated cardiomyopathy (DCM). We assessed myocardial contractile reserve using tissue Doppler strain rate imaging with dobutamine stress echocardiography in DCM patients.",
author = "Makoto Minoshima and Akiko Noda and Masakazu Kobayashi and Seiko Miyata and Akihiro Hirashiki and Takahiro Okumura and Hideo Izawa and Hideki Ishii and Takahisa Kondo and Toyoaki Murohara",
year = "2016",
month = "11",
day = "12",
doi = "10.1002/jcu.22376",
language = "English",
volume = "44",
pages = "555--560",
journal = "Journal of Clinical Ultrasound",
issn = "0091-2751",
publisher = "John Wiley and Sons Inc.",
number = "9",

}

Endomyocardial radial strain rate imaging during dobutamine stress echocardiography for the evaluation of contractile reserve in patients with dilated cardiomyopathy. / Minoshima, Makoto; Noda, Akiko; Kobayashi, Masakazu; Miyata, Seiko; Hirashiki, Akihiro; Okumura, Takahiro; Izawa, Hideo; Ishii, Hideki; Kondo, Takahisa; Murohara, Toyoaki.

In: Journal of clinical ultrasound : JCU, Vol. 44, No. 9, 12.11.2016, p. 555-560.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Endomyocardial radial strain rate imaging during dobutamine stress echocardiography for the evaluation of contractile reserve in patients with dilated cardiomyopathy

AU - Minoshima, Makoto

AU - Noda, Akiko

AU - Kobayashi, Masakazu

AU - Miyata, Seiko

AU - Hirashiki, Akihiro

AU - Okumura, Takahiro

AU - Izawa, Hideo

AU - Ishii, Hideki

AU - Kondo, Takahisa

AU - Murohara, Toyoaki

PY - 2016/11/12

Y1 - 2016/11/12

N2 - METHODS: Simultaneous echocardiography and left ventricular (LV) catheterization during dobutamine stress were performed in 20 patients with DCM, and echocardiography was performed in 31 control subjects. Dobutamine was infused at a starting dose of 5 μg/kg/min for 5 minutes and then at 10 μg/kg/min. Peak endomyocardial radial strain (ɛ) and systolic strain rate (SRsys ) measured with echocardiography and the maximum first derivative of LV pressure (LV dP/dtmax ) derived from catheterization were used as indices of contractility. Their percentage change from baseline to the dose of 10 μg/kg/min was calculated.RESULTS: The ɛ and SRsys were significantly smaller in DCM patients than in controls. The LV dP/dtmax , ɛ, and SRsys were significantly higher at the dose of 10 μg/kg/min than at baseline. The percentage change in SRsys was significantly correlated with the percentage change in LV dP/dtmax .CONCLUSIONS: Strain rate imaging during dobutamine stress in DCM might prove noninvasively informative for the evaluation of myocardial contractile reserve and provide insight into LV systolic dysfunction.PURPOSE: Myocardial contractile reserve is associated with clinical prognosis in patients with dilated cardiomyopathy (DCM). We assessed myocardial contractile reserve using tissue Doppler strain rate imaging with dobutamine stress echocardiography in DCM patients.

AB - METHODS: Simultaneous echocardiography and left ventricular (LV) catheterization during dobutamine stress were performed in 20 patients with DCM, and echocardiography was performed in 31 control subjects. Dobutamine was infused at a starting dose of 5 μg/kg/min for 5 minutes and then at 10 μg/kg/min. Peak endomyocardial radial strain (ɛ) and systolic strain rate (SRsys ) measured with echocardiography and the maximum first derivative of LV pressure (LV dP/dtmax ) derived from catheterization were used as indices of contractility. Their percentage change from baseline to the dose of 10 μg/kg/min was calculated.RESULTS: The ɛ and SRsys were significantly smaller in DCM patients than in controls. The LV dP/dtmax , ɛ, and SRsys were significantly higher at the dose of 10 μg/kg/min than at baseline. The percentage change in SRsys was significantly correlated with the percentage change in LV dP/dtmax .CONCLUSIONS: Strain rate imaging during dobutamine stress in DCM might prove noninvasively informative for the evaluation of myocardial contractile reserve and provide insight into LV systolic dysfunction.PURPOSE: Myocardial contractile reserve is associated with clinical prognosis in patients with dilated cardiomyopathy (DCM). We assessed myocardial contractile reserve using tissue Doppler strain rate imaging with dobutamine stress echocardiography in DCM patients.

UR - http://www.scopus.com/inward/record.url?scp=85028246437&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85028246437&partnerID=8YFLogxK

U2 - 10.1002/jcu.22376

DO - 10.1002/jcu.22376

M3 - Article

VL - 44

SP - 555

EP - 560

JO - Journal of Clinical Ultrasound

JF - Journal of Clinical Ultrasound

SN - 0091-2751

IS - 9

ER -