Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy

Naoki Omiya, Ayumu Taguchi, Kennosuke Shirai, Nobuyuki Mabuchi, Daigo Arakawa, Hironobu Kanazawa, Masayasu Ozeki, Masahiro Yamada, Masanao Nakamura, Akihiro Itoh, Yoshiki Hirooka, Yasumasa Niwa, Tetsuro Nagasaka, Masafumi Ito, Shinji Ohashi, Shozo Okamura, Hidemi Goto

Research output: Contribution to journalArticle

145 Citations (Scopus)

Abstract

Small-bowel enteroscopy with the double-balloon method was developed to improve access to the small intestine. This study evaluated the usefulness of this method for the resection of small-intestinal Peutz-Jeghers polyps. Two patients with Peutz-Jeghers syndrome underwent nonsurgical double-balloon enteroscopic resection of polyps throughout the small intestine. Multiple polyps in the jejunum were successfully resected via the oral route, as were the polyps in the ileum via the anal route. All 18 polyps (10-60 mm in size) were resected without subsequent bleeding or perforation. Histopathologically, 3 large polyps (>30 mm diameter) were hamartomas with adenomatous components. Double-balloon enteroscopy was safe and useful for the diagnosis and the treatment of Peutz-Jeghers polyps throughout the small intestine. Double-balloon enteroscopic polypectomy might preclude complications of Peutz-Jeghers syndrome, including intussusception, bleeding, and tumorogenesis, thereby obviating the need for multiple laparotomies.

Original languageEnglish
Pages (from-to)140-147
Number of pages8
JournalGastrointestinal Endoscopy
Volume61
Issue number1
DOIs
Publication statusPublished - 01-01-2005
Externally publishedYes

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Double-Balloon Enteroscopy
Polyps
Laparotomy
Small Intestine
Peutz-Jeghers Syndrome
Hemorrhage
Hamartoma
Intussusception
Jejunum
Ileum

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Omiya, Naoki ; Taguchi, Ayumu ; Shirai, Kennosuke ; Mabuchi, Nobuyuki ; Arakawa, Daigo ; Kanazawa, Hironobu ; Ozeki, Masayasu ; Yamada, Masahiro ; Nakamura, Masanao ; Itoh, Akihiro ; Hirooka, Yoshiki ; Niwa, Yasumasa ; Nagasaka, Tetsuro ; Ito, Masafumi ; Ohashi, Shinji ; Okamura, Shozo ; Goto, Hidemi. / Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy. In: Gastrointestinal Endoscopy. 2005 ; Vol. 61, No. 1. pp. 140-147.
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Omiya, N, Taguchi, A, Shirai, K, Mabuchi, N, Arakawa, D, Kanazawa, H, Ozeki, M, Yamada, M, Nakamura, M, Itoh, A, Hirooka, Y, Niwa, Y, Nagasaka, T, Ito, M, Ohashi, S, Okamura, S & Goto, H 2005, 'Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy', Gastrointestinal Endoscopy, vol. 61, no. 1, pp. 140-147. https://doi.org/10.1016/S0016-5107(04)02457-5

Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy. / Omiya, Naoki; Taguchi, Ayumu; Shirai, Kennosuke; Mabuchi, Nobuyuki; Arakawa, Daigo; Kanazawa, Hironobu; Ozeki, Masayasu; Yamada, Masahiro; Nakamura, Masanao; Itoh, Akihiro; Hirooka, Yoshiki; Niwa, Yasumasa; Nagasaka, Tetsuro; Ito, Masafumi; Ohashi, Shinji; Okamura, Shozo; Goto, Hidemi.

In: Gastrointestinal Endoscopy, Vol. 61, No. 1, 01.01.2005, p. 140-147.

Research output: Contribution to journalArticle

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T1 - Endoscopic resection of Peutz-Jeghers polyps throughout the small intestine at double-balloon enteroscopy without laparotomy

AU - Omiya, Naoki

AU - Taguchi, Ayumu

AU - Shirai, Kennosuke

AU - Mabuchi, Nobuyuki

AU - Arakawa, Daigo

AU - Kanazawa, Hironobu

AU - Ozeki, Masayasu

AU - Yamada, Masahiro

AU - Nakamura, Masanao

AU - Itoh, Akihiro

AU - Hirooka, Yoshiki

AU - Niwa, Yasumasa

AU - Nagasaka, Tetsuro

AU - Ito, Masafumi

AU - Ohashi, Shinji

AU - Okamura, Shozo

AU - Goto, Hidemi

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N2 - Small-bowel enteroscopy with the double-balloon method was developed to improve access to the small intestine. This study evaluated the usefulness of this method for the resection of small-intestinal Peutz-Jeghers polyps. Two patients with Peutz-Jeghers syndrome underwent nonsurgical double-balloon enteroscopic resection of polyps throughout the small intestine. Multiple polyps in the jejunum were successfully resected via the oral route, as were the polyps in the ileum via the anal route. All 18 polyps (10-60 mm in size) were resected without subsequent bleeding or perforation. Histopathologically, 3 large polyps (>30 mm diameter) were hamartomas with adenomatous components. Double-balloon enteroscopy was safe and useful for the diagnosis and the treatment of Peutz-Jeghers polyps throughout the small intestine. Double-balloon enteroscopic polypectomy might preclude complications of Peutz-Jeghers syndrome, including intussusception, bleeding, and tumorogenesis, thereby obviating the need for multiple laparotomies.

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