Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

Tsuyoshi Miyakawa, Takeshi Yagi, Masahiko Taniguchi, Hiroaki Matsuura, Kyoko Tateishi, Hiroaki Niki

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fynz fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.

Original languageEnglish
Pages (from-to)349-352
Number of pages4
JournalMolecular Brain Research
Volume28
Issue number2
DOIs
Publication statusPublished - 02-1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cellular and Molecular Neuroscience

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