Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

Tsuyoshi Miyakawa; Takeshi Yagi; Masahiko Taniguchi; Hiroaki Matsuura; Kyoko Tateishi; Hiroaki Niki

doi:10.1016/0169-328X(94)00251-9

Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

Tsuyoshi Miyakawa, Takeshi Yagi, Masahiko Taniguchi, Hiroaki Matsuura, Kyoko Tateishi, Hiroaki Niki

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fyn^z fyn^z) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.

Original language	English
Pages (from-to)	349-352
Number of pages	4
Journal	Molecular Brain Research
Volume	28
Issue number	2
DOIs	https://doi.org/10.1016/0169-328X(94)00251-9
Publication status	Published - 02-1995
Externally published	Yes

All Science Journal Classification (ASJC) codes

Molecular Biology
Cellular and Molecular Neuroscience

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10.1016/0169-328X(94)00251-9

Cite this

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title = "Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice",

abstract = "Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fynz fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.",

author = "Tsuyoshi Miyakawa and Takeshi Yagi and Masahiko Taniguchi and Hiroaki Matsuura and Kyoko Tateishi and Hiroaki Niki",

year = "1995",

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journal = "Molecular Brain Research",

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T1 - Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

AU - Miyakawa, Tsuyoshi

AU - Yagi, Takeshi

AU - Taniguchi, Masahiko

AU - Matsuura, Hiroaki

AU - Tateishi, Kyoko

AU - Niki, Hiroaki

PY - 1995/2

Y1 - 1995/2

N2 - Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fynz fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.

AB - Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant ( fynz fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.

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U2 - 10.1016/0169-328X(94)00251-9

DO - 10.1016/0169-328X(94)00251-9

M3 - Article

C2 - 7723633

AN - SCOPUS:0028895999

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JO - Molecular Brain Research

JF - Molecular Brain Research

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ER -

Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice

Abstract

All Science Journal Classification (ASJC) codes

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