@article{e56d17a6bcbc40fb928f565c94f87977,
title = "Establishment of a monitoring system to detect inhibition of mRNA processing",
abstract = "A number of proteins complete mRNA processing in the nucleus, thus, inhibitor of mRNA processing is worth finding to analyze the mechanism of mRNA maturation in detail. Here, we established a monitoring system for mRNA processing using a test compound, spliceostatin A (SSA), which inhibits mRNA splicing. This system should serve to facilitate the discovery of novel compounds from natural resources that inhibit mRNA processing.",
keywords = "Inhibitor, Luciferase reporter, MRNA processing, RNA-fluorescence in situ hybridyzation (FISH), Reverse transcription-polymerase chain reaction (RT-PCR)",
author = "Fujita, \{Ken Ichi\} and Masumi Okamura and Sachiko Nishimoto and Tomoya Kurihara and Keiko Momma and Yusaku Miyamae and Taiho Kambe and Masaya Nagao and Hiroshi Narita and Seiji Masuda",
note = "Funding Information: We thank Dr. M. Yoshida for kindly providing SSA. This work was supported in part by Grants-in-Aid from the Central Miso Research Institute, JST in research for adaptable and seamless technology transfer program through target-driven R\&D, exploratory research stage, and the Kieikai Research Foundation to S. M.",
year = "2012",
doi = "10.1271/bbb.120226",
language = "English",
volume = "76",
pages = "1248--1251",
journal = "Bioscience, Biotechnology and Biochemistry",
issn = "0916-8451",
publisher = "Oxford University Press",
number = "6",
}