Estimation of contrast of refraction contrast imaging compared with absorption imaging - Basic approach

Masatsugu Hirano, Katsuhito Yamasaki, Hiroshi Okada, Sohei Kitazawa, Riko Kitazawa, Yoshiharu Ohno, Takashi Sakurai, Takeshi Kondoh, Chiho Ohbayashi, Tetsuro Katafuchi, Sakan Maeda, Kazuro Sugimura, Shinichi Tamura

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Purpose: We discuss the usefulness of the refraction contrast method using highly parallel X-rays as a new approach to minute lung cancer detection. The advantages of refraction contrast images are discussed in terms of contrast, and a comparison is made with absorption images. Materials and Methods: We simulated refraction contrast imaging using globules with the density of water in air as models for minute lung cancer detection. The contrast intensified by bright and dark lines was compared on a globule with the contrast of absorption images. We adopted the Monte Carlo simulation to determine the strength of the profile curve of the photon counts at the detector. Results: The obtained contrasts were more intense by two to three digits than those obtainable with the absorption contrast imaging method. Conclusion: The contrast in refraction contrast imaging was more intense than that obtainable with absorption contrast imaging. A two to three digit improvement in contrast means that it is possible to greatly reduce the exposure dose necessary for imaging. Therefore, it is expected to become possible to detect the interfaces of soft tissues, which are difficult to capture with conventional absorption imaging, at low dosages and high resolution.

Original languageEnglish
Pages (from-to)89-96
Number of pages8
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Issue number2
Publication statusPublished - 03-2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Oncology


Dive into the research topics of 'Estimation of contrast of refraction contrast imaging compared with absorption imaging - Basic approach'. Together they form a unique fingerprint.

Cite this