TY - JOUR
T1 - Evaluating the Efficacy of Deep Learning Reconstruction in Reducing Radiation Dose for Computer-Aided Volumetry for Liver Tumor
T2 - A Phantom Study
AU - Nomura, Masahiko
AU - Ohno, Yoshiharu
AU - Ito, Yuya
AU - Kimata, Hirona
AU - Fujii, Kenji
AU - Akino, Naruomi
AU - Nagata, Hiroyuki
AU - Ueda, Takahiro
AU - Yoshikawa, Takeshi
AU - Takenaka, Daisuke
AU - Ozawa, Yoshiyuki
N1 - Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.
PY - 2024
Y1 - 2024
N2 - Objective The purpose of this study was to compare radiation dose reduction capability for accurate liver tumor measurements of a computer-Aided volumetry (CADv) software for filtered back projection (FBP), hybrid-Type iterative reconstruction (IR), mode-based iterative reconstruction (MBIR), and deep learning reconstruction (DLR) at a phantom study. Methods A commercially available anthropomorphic abdominal phantom was scanned five times with a 320-detector row CT at 600 mA, 400 mA, 200 mA, and 100 mA and reconstructed by four methods. Signal-To-noise ratios (SNRs) of all lesions within the arterial and portal-venous phase inserts were calculated, and SNR of the lesion phantom was compared with that of all reconstruction methods by means of Tukey's honestly significant difference (HSD) test. Then, tumor volume (V) of each nodule was automatically measured using commercially available CADv software. To compare dose reduction capability for each reconstruction method at both phases, mean differences between measured V and standard references were compared by Tukey's honestly significant difference test among the four different reconstruction methods on CT obtained at each of the four tube currents. Results With each of the tube currents, SNRs for MBIR and DLR were significantly higher than those for FBP and hybrid-Type IR (p < 0.05). At the arterial phase, the mean difference in V for the CT protocol obtained at 600 or 100 mA and reconstructed with DLR was significantly smaller than that for others (p < 0.05). At the portal-venous phase, the mean differences in V for the CT protocol obtained at 100 mA and reconstructed with hybrid-Type IR, MBIR, and DLR were significantly smaller than that for FBP (p < 0.05). Conclusions Findings of our phantom study show that reconstruction method had influence on CADv merits for abdominal CT with not only standard but also reduced dose examinations and that DLR can potentially yield better image quality and CADv measurements than FBP, hybrid-Type IR, or MBIR in this setting.
AB - Objective The purpose of this study was to compare radiation dose reduction capability for accurate liver tumor measurements of a computer-Aided volumetry (CADv) software for filtered back projection (FBP), hybrid-Type iterative reconstruction (IR), mode-based iterative reconstruction (MBIR), and deep learning reconstruction (DLR) at a phantom study. Methods A commercially available anthropomorphic abdominal phantom was scanned five times with a 320-detector row CT at 600 mA, 400 mA, 200 mA, and 100 mA and reconstructed by four methods. Signal-To-noise ratios (SNRs) of all lesions within the arterial and portal-venous phase inserts were calculated, and SNR of the lesion phantom was compared with that of all reconstruction methods by means of Tukey's honestly significant difference (HSD) test. Then, tumor volume (V) of each nodule was automatically measured using commercially available CADv software. To compare dose reduction capability for each reconstruction method at both phases, mean differences between measured V and standard references were compared by Tukey's honestly significant difference test among the four different reconstruction methods on CT obtained at each of the four tube currents. Results With each of the tube currents, SNRs for MBIR and DLR were significantly higher than those for FBP and hybrid-Type IR (p < 0.05). At the arterial phase, the mean difference in V for the CT protocol obtained at 600 or 100 mA and reconstructed with DLR was significantly smaller than that for others (p < 0.05). At the portal-venous phase, the mean differences in V for the CT protocol obtained at 100 mA and reconstructed with hybrid-Type IR, MBIR, and DLR were significantly smaller than that for FBP (p < 0.05). Conclusions Findings of our phantom study show that reconstruction method had influence on CADv merits for abdominal CT with not only standard but also reduced dose examinations and that DLR can potentially yield better image quality and CADv measurements than FBP, hybrid-Type IR, or MBIR in this setting.
KW - CT
KW - computer-Aided volumetry
KW - deep learning
KW - liver
KW - reconstruction
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U2 - 10.1097/RCT.0000000000001657
DO - 10.1097/RCT.0000000000001657
M3 - Article
C2 - 39511829
AN - SCOPUS:85209391786
SN - 0363-8715
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
ER -