Evaluation of Quality of Life After Simultaneous Pancreas and Kidney Transplantation From Living Donors Using Short Form 36

A. Suzuki, Takashi Kenmochi, M. Maruyama, K. Saigo, N. Akutsu, C. Iwashita, K. Otsuki, M. Miyazaki

Research output: Contribution to journalArticle

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Abstract

We performed the first case of simultaneous pancreas and kidney transplantation from a living donor (LDSPK) in 2004. We examined the quality of life (QOL) of performed 6 recipients and 5 donors among 8 LDSPK from 2004 to 2007 at our institution using Short Form 36. All recipients achieved insulin and hemodialysis independence after LDSPK with positive serum C-peptide levels. Before LDSPK, all scores of the 8 specific domains of the recipients were low (28.2 ± 10.6), indicating extremely poor QOL. Both the Physical and the Mental Component Summary Scores (PCS/MCS) quickly increased after LDSPK. PCS at 6, 12, and 24 months after LDSPK were significantly higher than the pretransplantation level. MCS were also significantly higher than the pretransplantation level. LDSPK showed prominent QOL improvement for the recipient. Complications were not observed in any donor. Although PCS decreased at 6 months after the operation, it recovered at 12 and at 24 months after the operation. MCS was maintained at more than 50 from 6 to 24 months after the operation. QOL was well preserved in the LDSPK donors despite the major surgery. In conclusion, LDSPK was confirmed to be a potent tool for treatment of type 1 diabetes mellitus patients with end-stage renal disease (ESRD) by complete normalization of glucose metabolism and renal function. In addition to these medical advantages, both their physical and mental QOL were improved by LDSPK.

Original languageEnglish
Pages (from-to)2565-2567
Number of pages3
JournalTransplantation Proceedings
Volume40
Issue number8
DOIs
Publication statusPublished - 01-10-2008

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Pancreas Transplantation
Living Donors
Kidney Transplantation
Quality of Life
Tissue Donors
C-Peptide
Quality Improvement
Type 1 Diabetes Mellitus
Chronic Kidney Failure
Renal Dialysis
Insulin
Kidney
Glucose
Serum

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation

Cite this

Suzuki, A. ; Kenmochi, Takashi ; Maruyama, M. ; Saigo, K. ; Akutsu, N. ; Iwashita, C. ; Otsuki, K. ; Miyazaki, M. / Evaluation of Quality of Life After Simultaneous Pancreas and Kidney Transplantation From Living Donors Using Short Form 36. In: Transplantation Proceedings. 2008 ; Vol. 40, No. 8. pp. 2565-2567.
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Evaluation of Quality of Life After Simultaneous Pancreas and Kidney Transplantation From Living Donors Using Short Form 36. / Suzuki, A.; Kenmochi, Takashi; Maruyama, M.; Saigo, K.; Akutsu, N.; Iwashita, C.; Otsuki, K.; Miyazaki, M.

In: Transplantation Proceedings, Vol. 40, No. 8, 01.10.2008, p. 2565-2567.

Research output: Contribution to journalArticle

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AU - Suzuki, A.

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