Examination of quantitative analysis method for cardiac amyloidosis by 99mTc-PYP scintigraphy

Shingo Tanahashi; Masakazu Tsujimoto; Tomoyuki Kurose; Masaki Uno; Masayoshi Sarai; Hideki Kawai; Hiroshi Toyama

doi:10.18888/rp.0000001699

Examination of quantitative analysis method for cardiac amyloidosis by 99mTc-PYP scintigraphy

Shingo Tanahashi, Masakazu Tsujimoto, Tomoyuki Kurose, Masaki Uno, Masayoshi Sarai, Hideki Kawai, Hiroshi Toyama

Research output: Contribution to journal › Article › peer-review

Abstract

99mTc—PYP scintigraphy has been used for diagnos-
ing transthyretin cardiac amyloidosis. However, its

quantitative analysis has not been fully established. We
aimed to examine the SUVs in the heart, aorta, and
lungs using SPECT/CT images, and compared them
with the conventional visual assessment. SUVmean in the
heart was higher in the amyloidosis group than in the
non amyloidosis group. Compared with SUVmean in the
heart, the ratio of SUVmean in the heart and aorta

(SUVratio(H/Ao))provided us a better cut—off for diagnos-
ing cardiac amyloidosis.

Original language	Japanese
Pages (from-to)	921
Number of pages	928
Journal	Japanese Journal of Clinical Radiology
DOIs	https://doi.org/10.18888/rp.0000001699
Publication status	Published - 09-2021

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10.18888/rp.0000001699

Cite this

@article{f5ca39ae84fc4a0b9a93b1d20f86f73e,

title = "Examination of quantitative analysis method for cardiac amyloidosis by 99mTc-PYP scintigraphy",

abstract = "99mTc—PYP scintigraphy has been used for diagnos- ing transthyretin cardiac amyloidosis. However, its quantitative analysis has not been fully established. We aimed to examine the SUVs in the heart, aorta, and lungs using SPECT/CT images, and compared them with the conventional visual assessment. SUVmean in the heart was higher in the amyloidosis group than in the non amyloidosis group. Compared with SUVmean in the heart, the ratio of SUVmean in the heart and aorta (SUVratio(H/Ao))provided us a better cut—off for diagnos- ing cardiac amyloidosis.",

author = "Shingo Tanahashi and Masakazu Tsujimoto and Tomoyuki Kurose and Masaki Uno and Masayoshi Sarai and Hideki Kawai and Hiroshi Toyama",

year = "2021",

month = sep,

doi = "10.18888/rp.0000001699",

language = "日本語",

pages = "921",

journal = "Japanese Journal of Clinical Radiology",

issn = "0009-9252",

publisher = "Kanehara Shuppan Co. Ltd",

}

TY - JOUR

T1 - Examination of quantitative analysis method for cardiac amyloidosis by 99mTc-PYP scintigraphy

AU - Tanahashi, Shingo

AU - Tsujimoto, Masakazu

AU - Kurose, Tomoyuki

AU - Uno, Masaki

AU - Sarai, Masayoshi

AU - Kawai, Hideki

AU - Toyama, Hiroshi

PY - 2021/9

Y1 - 2021/9

N2 - 99mTc—PYP scintigraphy has been used for diagnos- ing transthyretin cardiac amyloidosis. However, its quantitative analysis has not been fully established. We aimed to examine the SUVs in the heart, aorta, and lungs using SPECT/CT images, and compared them with the conventional visual assessment. SUVmean in the heart was higher in the amyloidosis group than in the non amyloidosis group. Compared with SUVmean in the heart, the ratio of SUVmean in the heart and aorta (SUVratio(H/Ao))provided us a better cut—off for diagnos- ing cardiac amyloidosis.

AB - 99mTc—PYP scintigraphy has been used for diagnos- ing transthyretin cardiac amyloidosis. However, its quantitative analysis has not been fully established. We aimed to examine the SUVs in the heart, aorta, and lungs using SPECT/CT images, and compared them with the conventional visual assessment. SUVmean in the heart was higher in the amyloidosis group than in the non amyloidosis group. Compared with SUVmean in the heart, the ratio of SUVmean in the heart and aorta (SUVratio(H/Ao))provided us a better cut—off for diagnos- ing cardiac amyloidosis.

U2 - 10.18888/rp.0000001699

DO - 10.18888/rp.0000001699

M3 - 学術論文

SN - 0009-9252

SP - 921

JO - Japanese Journal of Clinical Radiology

JF - Japanese Journal of Clinical Radiology

ER -