TY - JOUR
T1 - Excretion of herpes simplex virus type 2 glycoprotein D into the culture medium
AU - Murata, Takayuki
AU - Goshima, Fumi
AU - Takakuwa, Hiroki
AU - Nishiyama, Yukihiro
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2002/11/1
Y1 - 2002/11/1
N2 - Glycoprotein D (gD) of herpes simplex virus type 2 (HSV-2) was excreted from infected cells into the medium. Peptide mapping analysis and lectin binding assays suggested that the gD in the medium is secreted after full glycosylation and cleavage at its C terminus. Release of HSV-2 gD was inhibited by addition of either tunicamycin or brefeldin A, suggesting that the gD in the medium was secreted through the endoplasmic reticulum and Golgi apparatus.
AB - Glycoprotein D (gD) of herpes simplex virus type 2 (HSV-2) was excreted from infected cells into the medium. Peptide mapping analysis and lectin binding assays suggested that the gD in the medium is secreted after full glycosylation and cleavage at its C terminus. Release of HSV-2 gD was inhibited by addition of either tunicamycin or brefeldin A, suggesting that the gD in the medium was secreted through the endoplasmic reticulum and Golgi apparatus.
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U2 - 10.1099/0022-1317-83-11-2791
DO - 10.1099/0022-1317-83-11-2791
M3 - Article
C2 - 12388815
AN - SCOPUS:0036842072
SN - 0022-1317
VL - 83
SP - 2791
EP - 2795
JO - Journal of General Virology
JF - Journal of General Virology
IS - 11
ER -