Executive dysfunction is related with decreased frontal lobe blood flow in patients with subarachnoid haemorrhage

Ken Uchikawa, Makoto Inaba, Hiroshi Kagami, Shinya Ichimura, Toshiyuki Fujiwara, Tetsuya Tsuji, Yohei Otaka, Meigen Liu

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Objective: This study evaluated executive dysfunction in patients with subarachnoid haemorrhage (SAH) using the Behavioural Assessment of the Dysexecutive Syndrome (BADS) and correlated the occurrence of executive dysfunction with cerebral blood flow (CBF) reduction in the frontal lobe as assessed by single photon emission computed tomography (SPECT). Design: Correlational study. Subjects: Twenty-Two patients who underwent microsurgical clipping at least 3 months after SAH. Methods: This study evaluated the BADS and the Wechsler Adult Intelligence Scale-III (WAIS-III). In addition, it assessed activities of daily living (ADL). CBF was evaluated using SPECT. The patients were divided into the following groups according to the results of SPECT: (1) those with reduced CBF in the frontal lobe (reduced CBF group, n = 8) and (2) those with intact CBF (intact CBF group, n = 14). Results: The BADS score was significantly lower in the reduced CBF group compared with that of the intact CBF group, while there was no significant difference in the WAIS-III scores and ADL scale between the two groups. Conclusion: Although this result was conducted with a small sample size, executive dysfunction correlates with reduced CBF in the frontal lobes of SAH patients. A detailed evaluation of executive function is suggested in SAH patients, even if the patient's intelligence test and ADL scale reveal no abnormalities.

Original languageEnglish
Pages (from-to)15-19
Number of pages5
JournalBrain Injury
Volume28
Issue number1
DOIs
Publication statusPublished - 01-01-2014

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Cerebrovascular Circulation
Frontal Lobe
Subarachnoid Hemorrhage
Blood Group Antigens
Activities of Daily Living
Single-Photon Emission-Computed Tomography
Intelligence Tests
Executive Function
Intelligence
Sample Size

All Science Journal Classification (ASJC) codes

  • Neuroscience (miscellaneous)
  • Developmental and Educational Psychology
  • Clinical Neurology

Cite this

Uchikawa, K., Inaba, M., Kagami, H., Ichimura, S., Fujiwara, T., Tsuji, T., ... Liu, M. (2014). Executive dysfunction is related with decreased frontal lobe blood flow in patients with subarachnoid haemorrhage. Brain Injury, 28(1), 15-19. https://doi.org/10.3109/02699052.2013.847209
Uchikawa, Ken ; Inaba, Makoto ; Kagami, Hiroshi ; Ichimura, Shinya ; Fujiwara, Toshiyuki ; Tsuji, Tetsuya ; Otaka, Yohei ; Liu, Meigen. / Executive dysfunction is related with decreased frontal lobe blood flow in patients with subarachnoid haemorrhage. In: Brain Injury. 2014 ; Vol. 28, No. 1. pp. 15-19.
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abstract = "Objective: This study evaluated executive dysfunction in patients with subarachnoid haemorrhage (SAH) using the Behavioural Assessment of the Dysexecutive Syndrome (BADS) and correlated the occurrence of executive dysfunction with cerebral blood flow (CBF) reduction in the frontal lobe as assessed by single photon emission computed tomography (SPECT). Design: Correlational study. Subjects: Twenty-Two patients who underwent microsurgical clipping at least 3 months after SAH. Methods: This study evaluated the BADS and the Wechsler Adult Intelligence Scale-III (WAIS-III). In addition, it assessed activities of daily living (ADL). CBF was evaluated using SPECT. The patients were divided into the following groups according to the results of SPECT: (1) those with reduced CBF in the frontal lobe (reduced CBF group, n = 8) and (2) those with intact CBF (intact CBF group, n = 14). Results: The BADS score was significantly lower in the reduced CBF group compared with that of the intact CBF group, while there was no significant difference in the WAIS-III scores and ADL scale between the two groups. Conclusion: Although this result was conducted with a small sample size, executive dysfunction correlates with reduced CBF in the frontal lobes of SAH patients. A detailed evaluation of executive function is suggested in SAH patients, even if the patient's intelligence test and ADL scale reveal no abnormalities.",
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Executive dysfunction is related with decreased frontal lobe blood flow in patients with subarachnoid haemorrhage. / Uchikawa, Ken; Inaba, Makoto; Kagami, Hiroshi; Ichimura, Shinya; Fujiwara, Toshiyuki; Tsuji, Tetsuya; Otaka, Yohei; Liu, Meigen.

In: Brain Injury, Vol. 28, No. 1, 01.01.2014, p. 15-19.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Executive dysfunction is related with decreased frontal lobe blood flow in patients with subarachnoid haemorrhage

AU - Uchikawa, Ken

AU - Inaba, Makoto

AU - Kagami, Hiroshi

AU - Ichimura, Shinya

AU - Fujiwara, Toshiyuki

AU - Tsuji, Tetsuya

AU - Otaka, Yohei

AU - Liu, Meigen

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N2 - Objective: This study evaluated executive dysfunction in patients with subarachnoid haemorrhage (SAH) using the Behavioural Assessment of the Dysexecutive Syndrome (BADS) and correlated the occurrence of executive dysfunction with cerebral blood flow (CBF) reduction in the frontal lobe as assessed by single photon emission computed tomography (SPECT). Design: Correlational study. Subjects: Twenty-Two patients who underwent microsurgical clipping at least 3 months after SAH. Methods: This study evaluated the BADS and the Wechsler Adult Intelligence Scale-III (WAIS-III). In addition, it assessed activities of daily living (ADL). CBF was evaluated using SPECT. The patients were divided into the following groups according to the results of SPECT: (1) those with reduced CBF in the frontal lobe (reduced CBF group, n = 8) and (2) those with intact CBF (intact CBF group, n = 14). Results: The BADS score was significantly lower in the reduced CBF group compared with that of the intact CBF group, while there was no significant difference in the WAIS-III scores and ADL scale between the two groups. Conclusion: Although this result was conducted with a small sample size, executive dysfunction correlates with reduced CBF in the frontal lobes of SAH patients. A detailed evaluation of executive function is suggested in SAH patients, even if the patient's intelligence test and ADL scale reveal no abnormalities.

AB - Objective: This study evaluated executive dysfunction in patients with subarachnoid haemorrhage (SAH) using the Behavioural Assessment of the Dysexecutive Syndrome (BADS) and correlated the occurrence of executive dysfunction with cerebral blood flow (CBF) reduction in the frontal lobe as assessed by single photon emission computed tomography (SPECT). Design: Correlational study. Subjects: Twenty-Two patients who underwent microsurgical clipping at least 3 months after SAH. Methods: This study evaluated the BADS and the Wechsler Adult Intelligence Scale-III (WAIS-III). In addition, it assessed activities of daily living (ADL). CBF was evaluated using SPECT. The patients were divided into the following groups according to the results of SPECT: (1) those with reduced CBF in the frontal lobe (reduced CBF group, n = 8) and (2) those with intact CBF (intact CBF group, n = 14). Results: The BADS score was significantly lower in the reduced CBF group compared with that of the intact CBF group, while there was no significant difference in the WAIS-III scores and ADL scale between the two groups. Conclusion: Although this result was conducted with a small sample size, executive dysfunction correlates with reduced CBF in the frontal lobes of SAH patients. A detailed evaluation of executive function is suggested in SAH patients, even if the patient's intelligence test and ADL scale reveal no abnormalities.

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