TY - JOUR
T1 - Experimental validation of geometric and densitometric coronary measurements on the new generation cardiovascular angiography analysis system (caas ii)
AU - Haase, JÜRgen
AU - Escaned, Javier
AU - van Swijndregt, Eline Montauban
AU - Ozaki, Yukio
AU - Gronenschild, Ed
AU - Slager, Cornelis J.
AU - Serruys, Patrick W.
PY - 1993/10
Y1 - 1993/10
N2 - Computer‐assisted contour detection and videodensitometric cross sectional area assessment of coronary artery obstructions on the CAAS II system were validated in vitro and in vivo by angiographic cinefilm recording and automated measurement of stenosis phantoms (luminal diameter 0.5, 0.7, 1.0, 1.4, 1.9 mm) which were first inserted in a plexiglass model and then serially implanted in swine coronary arteries. “Obstruction diameter” (OD) and “obstruction area” (OA) values obtained from 10 in vitro and 19 in vivo images at the site of the artificial stenoses were compared with the true phantom dimensions. The in vitro assessment of OD yielded an accuracy of 0.00±0.11 mm (correlation coefficient: r = 0.98, y = 0.18 + 0.82x, standard error of estimate: SEE = 0.08), whereas the in vivo measurement of OD gave an accuracy of −0.01 ± 0.18 mm (r = 0.94, y = 0.22 + 0.82x, SEE = 0.15). The assessment of OA gave an accuracy of −0.08 ± 0.21 mm2 in vitro (r = 0.97, y = 0.08 + 0.99x, SEE = 0.22) and −0.22 ± 0.32 mm2 in vivo (r = 0.95, y = 0.21 + 1.01x, SEE = 0.33). The mean reproducibility was ±0.09 mm for geometric measurements and ±0.21 mm2 for videodensitometric assessments, respectively. Thus, due to inherent limitations of the imaging chain, the reliability of geometric coronary measurements is still far superior to videodensitometric assessments of vessel cross sectional areas. © 1993 Wiiey‐Liss, Inc.
AB - Computer‐assisted contour detection and videodensitometric cross sectional area assessment of coronary artery obstructions on the CAAS II system were validated in vitro and in vivo by angiographic cinefilm recording and automated measurement of stenosis phantoms (luminal diameter 0.5, 0.7, 1.0, 1.4, 1.9 mm) which were first inserted in a plexiglass model and then serially implanted in swine coronary arteries. “Obstruction diameter” (OD) and “obstruction area” (OA) values obtained from 10 in vitro and 19 in vivo images at the site of the artificial stenoses were compared with the true phantom dimensions. The in vitro assessment of OD yielded an accuracy of 0.00±0.11 mm (correlation coefficient: r = 0.98, y = 0.18 + 0.82x, standard error of estimate: SEE = 0.08), whereas the in vivo measurement of OD gave an accuracy of −0.01 ± 0.18 mm (r = 0.94, y = 0.22 + 0.82x, SEE = 0.15). The assessment of OA gave an accuracy of −0.08 ± 0.21 mm2 in vitro (r = 0.97, y = 0.08 + 0.99x, SEE = 0.22) and −0.22 ± 0.32 mm2 in vivo (r = 0.95, y = 0.21 + 1.01x, SEE = 0.33). The mean reproducibility was ±0.09 mm for geometric measurements and ±0.21 mm2 for videodensitometric assessments, respectively. Thus, due to inherent limitations of the imaging chain, the reliability of geometric coronary measurements is still far superior to videodensitometric assessments of vessel cross sectional areas. © 1993 Wiiey‐Liss, Inc.
UR - http://www.scopus.com/inward/record.url?scp=0027383276&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027383276&partnerID=8YFLogxK
U2 - 10.1002/ccd.1810300205
DO - 10.1002/ccd.1810300205
M3 - Article
C2 - 8221861
AN - SCOPUS:0027383276
SN - 0098-6569
VL - 30
SP - 104
EP - 114
JO - Catheterization and Cardiovascular Diagnosis
JF - Catheterization and Cardiovascular Diagnosis
IS - 2
ER -