Expression of keratan sulfate at the arthroplasty surface after cup arthroplasty

Harumoto Yamada, Toshiyuki Kikuchi, Mitsuhiro Morita, Osamu Henmi, Kyosuke Fujikawa, Osuke Washimi, Nobuki Terada, Tsuneo Seki

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Fibrous tissue which regenerated on the acetabular arthroplasty surface was obtained from a 52-year-old woman who underwent total hip replacement after cup arthroplasty. The histological features of this newly formed fibrous tissue and expression of keratan sulfate, which is a characteristic matrix component of articular cartilage, were studied. Microscopic observation revealed that the arthroplasty surface consisted mainly of fibrous tissue which did not show metachromasia with toluidine blue staining, but there were many nodular structures communicating with the bone marrow. Immunostaining for keratan sulfate revealed clear positive staining around the cells of the nodular structures communicating with the bone marrow, while only weakly positive staining was observed in the superficial layer of the loose fibrous tissue. The present study revealed marked formation of articular cartilaginous tissue in areas having good communication with the bone marrow, which indicates that maintenance of this communication may be necessary to improve the outcome of cup arthroplasty.

Original languageEnglish
Pages (from-to)473-475
Number of pages3
JournalArchives of Orthopaedic and Trauma Surgery
Volume120
Issue number7-8
DOIs
Publication statusPublished - 25-07-2000

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Keratan Sulfate
Arthroplasty
Bone Marrow
Staining and Labeling
Tolonium Chloride
Hip Replacement Arthroplasties
Articular Cartilage
Joints
Communication
Maintenance

All Science Journal Classification (ASJC) codes

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Yamada, Harumoto ; Kikuchi, Toshiyuki ; Morita, Mitsuhiro ; Henmi, Osamu ; Fujikawa, Kyosuke ; Washimi, Osuke ; Terada, Nobuki ; Seki, Tsuneo. / Expression of keratan sulfate at the arthroplasty surface after cup arthroplasty. In: Archives of Orthopaedic and Trauma Surgery. 2000 ; Vol. 120, No. 7-8. pp. 473-475.
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Yamada, H, Kikuchi, T, Morita, M, Henmi, O, Fujikawa, K, Washimi, O, Terada, N & Seki, T 2000, 'Expression of keratan sulfate at the arthroplasty surface after cup arthroplasty', Archives of Orthopaedic and Trauma Surgery, vol. 120, no. 7-8, pp. 473-475. https://doi.org/10.1007/s004029900099

Expression of keratan sulfate at the arthroplasty surface after cup arthroplasty. / Yamada, Harumoto; Kikuchi, Toshiyuki; Morita, Mitsuhiro; Henmi, Osamu; Fujikawa, Kyosuke; Washimi, Osuke; Terada, Nobuki; Seki, Tsuneo.

In: Archives of Orthopaedic and Trauma Surgery, Vol. 120, No. 7-8, 25.07.2000, p. 473-475.

Research output: Contribution to journalArticle

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AU - Yamada, Harumoto

AU - Kikuchi, Toshiyuki

AU - Morita, Mitsuhiro

AU - Henmi, Osamu

AU - Fujikawa, Kyosuke

AU - Washimi, Osuke

AU - Terada, Nobuki

AU - Seki, Tsuneo

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Y1 - 2000/7/25

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