Fas antigen mRNA induction in postischemic murine brain

Tomohiro Matsuyama, Ryuji Hata, Masafumi Tagaya, Yoshihiro Yamamoto, Taisuke Nakajima, Jun ichi Furuyama, Akio Wanaka, Minoru Sugita

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.

Original languageEnglish
Pages (from-to)342-346
Number of pages5
JournalBrain Research
Volume657
Issue number1-2
DOIs
Publication statusPublished - 19-09-1994

Fingerprint

CD95 Antigens
Messenger RNA
Brain
Inbred BALB C Mouse
Transient Ischemic Attack
Brain Ischemia
Northern Blotting
Cell Death

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Matsuyama, T., Hata, R., Tagaya, M., Yamamoto, Y., Nakajima, T., Furuyama, J. I., ... Sugita, M. (1994). Fas antigen mRNA induction in postischemic murine brain. Brain Research, 657(1-2), 342-346. https://doi.org/10.1016/0006-8993(94)90989-X
Matsuyama, Tomohiro ; Hata, Ryuji ; Tagaya, Masafumi ; Yamamoto, Yoshihiro ; Nakajima, Taisuke ; Furuyama, Jun ichi ; Wanaka, Akio ; Sugita, Minoru. / Fas antigen mRNA induction in postischemic murine brain. In: Brain Research. 1994 ; Vol. 657, No. 1-2. pp. 342-346.
@article{434d66c4ca0a4b68a6c02d6165e19299,
title = "Fas antigen mRNA induction in postischemic murine brain",
abstract = "Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.",
author = "Tomohiro Matsuyama and Ryuji Hata and Masafumi Tagaya and Yoshihiro Yamamoto and Taisuke Nakajima and Furuyama, {Jun ichi} and Akio Wanaka and Minoru Sugita",
year = "1994",
month = "9",
day = "19",
doi = "10.1016/0006-8993(94)90989-X",
language = "English",
volume = "657",
pages = "342--346",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "1-2",

}

Matsuyama, T, Hata, R, Tagaya, M, Yamamoto, Y, Nakajima, T, Furuyama, JI, Wanaka, A & Sugita, M 1994, 'Fas antigen mRNA induction in postischemic murine brain', Brain Research, vol. 657, no. 1-2, pp. 342-346. https://doi.org/10.1016/0006-8993(94)90989-X

Fas antigen mRNA induction in postischemic murine brain. / Matsuyama, Tomohiro; Hata, Ryuji; Tagaya, Masafumi; Yamamoto, Yoshihiro; Nakajima, Taisuke; Furuyama, Jun ichi; Wanaka, Akio; Sugita, Minoru.

In: Brain Research, Vol. 657, No. 1-2, 19.09.1994, p. 342-346.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Fas antigen mRNA induction in postischemic murine brain

AU - Matsuyama, Tomohiro

AU - Hata, Ryuji

AU - Tagaya, Masafumi

AU - Yamamoto, Yoshihiro

AU - Nakajima, Taisuke

AU - Furuyama, Jun ichi

AU - Wanaka, Akio

AU - Sugita, Minoru

PY - 1994/9/19

Y1 - 1994/9/19

N2 - Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.

AB - Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.

UR - http://www.scopus.com/inward/record.url?scp=0028120349&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028120349&partnerID=8YFLogxK

U2 - 10.1016/0006-8993(94)90989-X

DO - 10.1016/0006-8993(94)90989-X

M3 - Article

C2 - 7529644

AN - SCOPUS:0028120349

VL - 657

SP - 342

EP - 346

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1-2

ER -

Matsuyama T, Hata R, Tagaya M, Yamamoto Y, Nakajima T, Furuyama JI et al. Fas antigen mRNA induction in postischemic murine brain. Brain Research. 1994 Sep 19;657(1-2):342-346. https://doi.org/10.1016/0006-8993(94)90989-X