Fas antigen mRNA induction in postischemic murine brain

Tomohiro Matsuyama; Ryuji Hata; Masafumi Tagaya; Yoshihiro Yamamoto; Taisuke Nakajima; Jun ichi Furuyama; Akio Wanaka; Minoru Sugita

doi:10.1016/0006-8993(94)90989-X

Fas antigen mRNA induction in postischemic murine brain

Tomohiro Matsuyama, Ryuji Hata, Masafumi Tagaya, Yoshihiro Yamamoto, Taisuke Nakajima, Jun ichi Furuyama, Akio Wanaka, Minoru Sugita

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72 Citations (Scopus)

Abstract

Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.

Original language	English
Pages (from-to)	342-346
Number of pages	5
Journal	Brain Research
Volume	657
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(94)90989-X
Publication status	Published - 19-09-1994
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(94)90989-X

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title = "Fas antigen mRNA induction in postischemic murine brain",

abstract = "Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.",

author = "Tomohiro Matsuyama and Ryuji Hata and Masafumi Tagaya and Yoshihiro Yamamoto and Taisuke Nakajima and Furuyama, \{Jun ichi\} and Akio Wanaka and Minoru Sugita",

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T1 - Fas antigen mRNA induction in postischemic murine brain

AU - Matsuyama, Tomohiro

AU - Hata, Ryuji

AU - Tagaya, Masafumi

AU - Yamamoto, Yoshihiro

AU - Nakajima, Taisuke

AU - Furuyama, Jun ichi

AU - Wanaka, Akio

AU - Sugita, Minoru

PY - 1994/9/19

Y1 - 1994/9/19

N2 - Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.

AB - Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.

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U2 - 10.1016/0006-8993(94)90989-X

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M3 - Article

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JO - Brain Research

JF - Brain Research

IS - 1-2

ER -

Fas antigen mRNA induction in postischemic murine brain

Abstract

All Science Journal Classification (ASJC) codes

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