Fatal encephalitis/encephalopathy in primary human herpesvirus-6 infection

Y. Asano, T. Yoshikawa, Y. Kajita, R. Ogura, S. Suga, T. Yazaki, T. Nakashima, A. Yamada, T. Kurata

Research output: Contribution to journalArticlepeer-review

154 Citations (Scopus)


An encephalitic illness with a fatal outcome occurred in a 9 month old girl with virologically confirmed exanthem subitum. Human herpesvirus- 6 (HHV-6) DNA was found in the cerebrospinal fluid at the acute stage of the disease by the polymerase chain reaction, but the virus antigen was not detected in her brain tissue. This suggests that HHV-6-induced encephalitis/encephalopathy may be due to a non-infectious process.

Original languageEnglish
Pages (from-to)1484-1485
Number of pages2
JournalArchives of Disease in Childhood
Issue number12
Publication statusPublished - 1992

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health


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