Feasibility of newly developed endoscopic ultrasound with zone sonography technology for diagnosis of pancreatic diseases

Yoshiki Hirooka, Akihiro Itoh, Hiroki Kawashima, Eizaburo Ohno, Yuya Itoh, Yosuke Nakamura, Takeshi Hiramatsu, Hiroyuki Sugimoto, Hajime Sumi, Daijiro Hayashi, Naoki Ohmiya, Ryoji Miyahara, Masanao Nakamura, Kohei Funasaka, Masatoshi Ishigami, Yoshiaki Katano, Hidemi Goto

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Background/Aims: To confirm the feasibility of using newly developed endoscopic ultrasound (EUS) with Zone sonographyTM technology (ZST; Fujifilm Corp.). Methods: Seventy-five patients with pancreatic disorders were enrolled: 45 with intraductal papillary mucinous neoplasm; 15 with ductal carcinoma; five with neuroendocrine tumors; three with serous cystic neoplasms; and seven with simple cysts. The endoscopes used were EG-530UR2 and EG-530UT2 (Fujifilm Corp.). Two items were evaluated: visualization depth among four frequencies and image quality after automatic adjustment of sound speed (AASS), assessed using a 5-scale Likert scale by two endosonographers blinded to disease status. Because sound speed could be manually controlled, besides AASS, image quality at sound speeds of 1,440 and 1,600 m/sec were also assessed. Results: In all cases, sufficient images were obtained in the range of 3 cm from the EUS probe. Judgments of image quality before AASS were 3.49±0.50, 3.65±0.48, respectively. After AASS, A and B scored 4.36±0.48 and 4.40±0.49 (p<0.0001). There were significant differences in the data before and after AASS and plus 60 m/sec, but no significant difference between the datasets were seen after AASS and at sound speeds manually set for minus 100 m/sec. Conclusions: EUS with ZST was shown to be feasible in this preliminary experiment. Further evaluation of this novel technology is necessary and awaited.

Original languageEnglish
Pages (from-to)486-491
Number of pages6
JournalGut and Liver
Issue number4
Publication statusPublished - 07-2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology


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