TY - JOUR
T1 - Feasibility of Real‐Time Central Surgical Review for Patients with Advanced‐Stage Hepatoblastoma in the JPLT3 Trial
AU - Hishiki, Tomoro
AU - Honda, Shohei
AU - Takama, Yuichi
AU - Inomata, Yukihiro
AU - Okajima, Hideaki
AU - Hoshino, Ken
AU - Suzuki, Tatsuya
AU - Souzaki, Ryota
AU - Wada, Motoshi
AU - Kasahara, Mureo
AU - Mizuta, Koichi
AU - Oue, Takaharu
AU - Yokoi, Akiko
AU - Kazama, Takuro
AU - Komatsu, Shugo
AU - Saeki, Isamu
AU - Miyazaki, Osamu
AU - Takimoto, Tetsuya
AU - Ida, Kohmei
AU - Watanabe, Kenichiro
AU - Hiyama, Eiso
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/2
Y1 - 2022/2
N2 - In the JPLT3 study, a real‐time central surgical reviewing (CSR) system was employed aimed at facilitating early referral of candidates for liver transplantation (LTx) to centers with pediatric LTx services. The expected consequence was surgery, including LTx, conducted at the appro-priate time in all cases. This study aimed to review the effect of CSR on institutional surgical deci-sions in cases enrolled in the JPLT3 study. Real‐time CSR was performed in cases in which complex surgeries were expected, using images obtained after two courses of preoperative chemotherapy. Using the cloud‐based remote image viewing system, an expert panel consisting of pediatric and transplant surgeons reviewed the images and commented on the expected surgical strategy or the necessity of transferring the patient to a transplant unit. The results were summarized and reported to the treating institutions. A total of 41 reviews were conducted for 35 patients, and 16 cases were evaluated as possible candidates for LTx, with the treating institutions being advised to consult a transplant center. Most of the reviewed cases promptly underwent definitive liver surgeries, including LTx per protocol.
AB - In the JPLT3 study, a real‐time central surgical reviewing (CSR) system was employed aimed at facilitating early referral of candidates for liver transplantation (LTx) to centers with pediatric LTx services. The expected consequence was surgery, including LTx, conducted at the appro-priate time in all cases. This study aimed to review the effect of CSR on institutional surgical deci-sions in cases enrolled in the JPLT3 study. Real‐time CSR was performed in cases in which complex surgeries were expected, using images obtained after two courses of preoperative chemotherapy. Using the cloud‐based remote image viewing system, an expert panel consisting of pediatric and transplant surgeons reviewed the images and commented on the expected surgical strategy or the necessity of transferring the patient to a transplant unit. The results were summarized and reported to the treating institutions. A total of 41 reviews were conducted for 35 patients, and 16 cases were evaluated as possible candidates for LTx, with the treating institutions being advised to consult a transplant center. Most of the reviewed cases promptly underwent definitive liver surgeries, including LTx per protocol.
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U2 - 10.3390/children9020234
DO - 10.3390/children9020234
M3 - Article
AN - SCOPUS:85124666185
SN - 2227-9067
VL - 9
JO - Children
JF - Children
IS - 2
M1 - 234
ER -