Feasibility of tissue elastography using transcutaneous ultrasonography for the diagnosis of pancreatic diseases

Hiroki Uchida, Yoshiki Hirooka, Akihiro Itoh, Hiroki Kawashima, Kazuo Hara, Koji Nonogaki, Toshifumi Kasugai, Eizaburo Ohno, Naoki Ohmiya, Yasumasa Niwa, Yoshiaki Katano, Masatoshi Ishigami, Hidemi Goto

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Abstract

Objectives:: We investigated the feasibility of using real-time tissue elastography (EG) with transcutaneous ultrasonography (EG-US) for pancreatic diseases. Methods:: A preliminary study (phase I) and a prospective (phase II) study were conducted. Phase I: subjects were 10 volunteers, 5 with cancer, 2 with endocrine tumor, 5 with chronic pancreatitis, 14 with intraductal papillary-mucinous neoplasm. To determine the characteristic EG images (diagnostic criteria for phase II), B-mode images were compared with EG images and histopathologic findings. Phase II: 53 consecutive patients were enrolled. The visualization rate by EG-US in lesions visualized by B mode was assessed, and the correct diagnosis rate by B mode alone (B diagnosis) or in combination with EG-US was evaluated. Results:: Phase I: normal parenchyma was a homogeneous color. In cancer, EG-US showed a markedly hard area with soft spots inside. Endocrine tumor was uniform and soft comparable to parenchyma. Chronic pancreatitis showed a mixture of various colors. Phase II: we identified 77.4% (41/53) of the lesions and observed 60.0% (15/25) of the cancers, 100% (3/3) of the endocrine tumor, 92.0% (23/25) of the cases of chronic pancreatitis cases on EG-US. The B-diagnosis rates ranged from about 70% to 80%. The diagnosis rates of the combination were more than 90% of lesions of each type. Conclusions:: The EG-US is feasible in the diagnosis of pancreatic diseases.

Original languageEnglish
Pages (from-to)17-22
Number of pages6
JournalPancreas
Volume38
Issue number1
DOIs
Publication statusPublished - 01-01-2009

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Elasticity Imaging Techniques
Pancreatic Diseases
Ultrasonography
Chronic Pancreatitis
Neoplasms
Color
Volunteers

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Cite this

Uchida, H., Hirooka, Y., Itoh, A., Kawashima, H., Hara, K., Nonogaki, K., ... Goto, H. (2009). Feasibility of tissue elastography using transcutaneous ultrasonography for the diagnosis of pancreatic diseases. Pancreas, 38(1), 17-22. https://doi.org/10.1097/MPA.0b013e318184db78
Uchida, Hiroki ; Hirooka, Yoshiki ; Itoh, Akihiro ; Kawashima, Hiroki ; Hara, Kazuo ; Nonogaki, Koji ; Kasugai, Toshifumi ; Ohno, Eizaburo ; Ohmiya, Naoki ; Niwa, Yasumasa ; Katano, Yoshiaki ; Ishigami, Masatoshi ; Goto, Hidemi. / Feasibility of tissue elastography using transcutaneous ultrasonography for the diagnosis of pancreatic diseases. In: Pancreas. 2009 ; Vol. 38, No. 1. pp. 17-22.
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abstract = "Objectives:: We investigated the feasibility of using real-time tissue elastography (EG) with transcutaneous ultrasonography (EG-US) for pancreatic diseases. Methods:: A preliminary study (phase I) and a prospective (phase II) study were conducted. Phase I: subjects were 10 volunteers, 5 with cancer, 2 with endocrine tumor, 5 with chronic pancreatitis, 14 with intraductal papillary-mucinous neoplasm. To determine the characteristic EG images (diagnostic criteria for phase II), B-mode images were compared with EG images and histopathologic findings. Phase II: 53 consecutive patients were enrolled. The visualization rate by EG-US in lesions visualized by B mode was assessed, and the correct diagnosis rate by B mode alone (B diagnosis) or in combination with EG-US was evaluated. Results:: Phase I: normal parenchyma was a homogeneous color. In cancer, EG-US showed a markedly hard area with soft spots inside. Endocrine tumor was uniform and soft comparable to parenchyma. Chronic pancreatitis showed a mixture of various colors. Phase II: we identified 77.4{\%} (41/53) of the lesions and observed 60.0{\%} (15/25) of the cancers, 100{\%} (3/3) of the endocrine tumor, 92.0{\%} (23/25) of the cases of chronic pancreatitis cases on EG-US. The B-diagnosis rates ranged from about 70{\%} to 80{\%}. The diagnosis rates of the combination were more than 90{\%} of lesions of each type. Conclusions:: The EG-US is feasible in the diagnosis of pancreatic diseases.",
author = "Hiroki Uchida and Yoshiki Hirooka and Akihiro Itoh and Hiroki Kawashima and Kazuo Hara and Koji Nonogaki and Toshifumi Kasugai and Eizaburo Ohno and Naoki Ohmiya and Yasumasa Niwa and Yoshiaki Katano and Masatoshi Ishigami and Hidemi Goto",
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Uchida, H, Hirooka, Y, Itoh, A, Kawashima, H, Hara, K, Nonogaki, K, Kasugai, T, Ohno, E, Ohmiya, N, Niwa, Y, Katano, Y, Ishigami, M & Goto, H 2009, 'Feasibility of tissue elastography using transcutaneous ultrasonography for the diagnosis of pancreatic diseases', Pancreas, vol. 38, no. 1, pp. 17-22. https://doi.org/10.1097/MPA.0b013e318184db78

Feasibility of tissue elastography using transcutaneous ultrasonography for the diagnosis of pancreatic diseases. / Uchida, Hiroki; Hirooka, Yoshiki; Itoh, Akihiro; Kawashima, Hiroki; Hara, Kazuo; Nonogaki, Koji; Kasugai, Toshifumi; Ohno, Eizaburo; Ohmiya, Naoki; Niwa, Yasumasa; Katano, Yoshiaki; Ishigami, Masatoshi; Goto, Hidemi.

In: Pancreas, Vol. 38, No. 1, 01.01.2009, p. 17-22.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Feasibility of tissue elastography using transcutaneous ultrasonography for the diagnosis of pancreatic diseases

AU - Uchida, Hiroki

AU - Hirooka, Yoshiki

AU - Itoh, Akihiro

AU - Kawashima, Hiroki

AU - Hara, Kazuo

AU - Nonogaki, Koji

AU - Kasugai, Toshifumi

AU - Ohno, Eizaburo

AU - Ohmiya, Naoki

AU - Niwa, Yasumasa

AU - Katano, Yoshiaki

AU - Ishigami, Masatoshi

AU - Goto, Hidemi

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Objectives:: We investigated the feasibility of using real-time tissue elastography (EG) with transcutaneous ultrasonography (EG-US) for pancreatic diseases. Methods:: A preliminary study (phase I) and a prospective (phase II) study were conducted. Phase I: subjects were 10 volunteers, 5 with cancer, 2 with endocrine tumor, 5 with chronic pancreatitis, 14 with intraductal papillary-mucinous neoplasm. To determine the characteristic EG images (diagnostic criteria for phase II), B-mode images were compared with EG images and histopathologic findings. Phase II: 53 consecutive patients were enrolled. The visualization rate by EG-US in lesions visualized by B mode was assessed, and the correct diagnosis rate by B mode alone (B diagnosis) or in combination with EG-US was evaluated. Results:: Phase I: normal parenchyma was a homogeneous color. In cancer, EG-US showed a markedly hard area with soft spots inside. Endocrine tumor was uniform and soft comparable to parenchyma. Chronic pancreatitis showed a mixture of various colors. Phase II: we identified 77.4% (41/53) of the lesions and observed 60.0% (15/25) of the cancers, 100% (3/3) of the endocrine tumor, 92.0% (23/25) of the cases of chronic pancreatitis cases on EG-US. The B-diagnosis rates ranged from about 70% to 80%. The diagnosis rates of the combination were more than 90% of lesions of each type. Conclusions:: The EG-US is feasible in the diagnosis of pancreatic diseases.

AB - Objectives:: We investigated the feasibility of using real-time tissue elastography (EG) with transcutaneous ultrasonography (EG-US) for pancreatic diseases. Methods:: A preliminary study (phase I) and a prospective (phase II) study were conducted. Phase I: subjects were 10 volunteers, 5 with cancer, 2 with endocrine tumor, 5 with chronic pancreatitis, 14 with intraductal papillary-mucinous neoplasm. To determine the characteristic EG images (diagnostic criteria for phase II), B-mode images were compared with EG images and histopathologic findings. Phase II: 53 consecutive patients were enrolled. The visualization rate by EG-US in lesions visualized by B mode was assessed, and the correct diagnosis rate by B mode alone (B diagnosis) or in combination with EG-US was evaluated. Results:: Phase I: normal parenchyma was a homogeneous color. In cancer, EG-US showed a markedly hard area with soft spots inside. Endocrine tumor was uniform and soft comparable to parenchyma. Chronic pancreatitis showed a mixture of various colors. Phase II: we identified 77.4% (41/53) of the lesions and observed 60.0% (15/25) of the cancers, 100% (3/3) of the endocrine tumor, 92.0% (23/25) of the cases of chronic pancreatitis cases on EG-US. The B-diagnosis rates ranged from about 70% to 80%. The diagnosis rates of the combination were more than 90% of lesions of each type. Conclusions:: The EG-US is feasible in the diagnosis of pancreatic diseases.

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