[First outbreak report of VIM-1 metallo-beta-lactamase producing Pseudomonas aeruginosa in Japan].

Kanji Miki; Hiroshi Takegawa; Masaaki Etoh; Michio Hayashi; Tsunekazu Haruta; Kunikazu Yamane; Yoshichika Arakawa

doi:10.11150/kansenshogakuzasshi.84.721

[First outbreak report of VIM-1 metallo-beta-lactamase producing Pseudomonas aeruginosa in Japan].

Kanji Miki, Hiroshi Takegawa, Masaaki Etoh, Michio Hayashi, Tsunekazu Haruta, Kunikazu Yamane, Yoshichika Arakawa

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

VIM-1 metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa was isolated from 35 Kobe City Medical Center General Hospital patients from September 2007 to July 2008. All but one were highly resistant to all beta-lactams, aminoglycoside, and fluoroquinolone, and one susceptible to amikacin. Strains negative to a disk diffusion screening test using sodium mercaptoacetate for detecting MBL numbered 35. PCR for MBL indicated all strains were positive for bla(VIWM-1). These strains were indistinguishable by pulsed-field gel electrophoresis, indicating an outbreak of infections caused by VIM-1 MBL producing Pseudomonas aeruginosa. After intervention to control contact, the outbreak was controlled.

Original language	English
Pages (from-to)	721-726
Number of pages	6
Journal	Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases
Volume	84
Issue number	6
DOIs	https://doi.org/10.11150/kansenshogakuzasshi.84.721
Publication status	Published - 11-2010
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine

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10.11150/kansenshogakuzasshi.84.721

Cite this

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title = "[First outbreak report of VIM-1 metallo-beta-lactamase producing Pseudomonas aeruginosa in Japan].",

abstract = "VIM-1 metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa was isolated from 35 Kobe City Medical Center General Hospital patients from September 2007 to July 2008. All but one were highly resistant to all beta-lactams, aminoglycoside, and fluoroquinolone, and one susceptible to amikacin. Strains negative to a disk diffusion screening test using sodium mercaptoacetate for detecting MBL numbered 35. PCR for MBL indicated all strains were positive for bla(VIWM-1). These strains were indistinguishable by pulsed-field gel electrophoresis, indicating an outbreak of infections caused by VIM-1 MBL producing Pseudomonas aeruginosa. After intervention to control contact, the outbreak was controlled.",

author = "Kanji Miki and Hiroshi Takegawa and Masaaki Etoh and Michio Hayashi and Tsunekazu Haruta and Kunikazu Yamane and Yoshichika Arakawa",

year = "2010",

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doi = "10.11150/kansenshogakuzasshi.84.721",

language = "English",

volume = "84",

pages = "721--726",

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T1 - [First outbreak report of VIM-1 metallo-beta-lactamase producing Pseudomonas aeruginosa in Japan].

AU - Miki, Kanji

AU - Takegawa, Hiroshi

AU - Etoh, Masaaki

AU - Hayashi, Michio

AU - Haruta, Tsunekazu

AU - Yamane, Kunikazu

AU - Arakawa, Yoshichika

PY - 2010/11

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AB - VIM-1 metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa was isolated from 35 Kobe City Medical Center General Hospital patients from September 2007 to July 2008. All but one were highly resistant to all beta-lactams, aminoglycoside, and fluoroquinolone, and one susceptible to amikacin. Strains negative to a disk diffusion screening test using sodium mercaptoacetate for detecting MBL numbered 35. PCR for MBL indicated all strains were positive for bla(VIWM-1). These strains were indistinguishable by pulsed-field gel electrophoresis, indicating an outbreak of infections caused by VIM-1 MBL producing Pseudomonas aeruginosa. After intervention to control contact, the outbreak was controlled.

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[First outbreak report of VIM-1 metallo-beta-lactamase producing Pseudomonas aeruginosa in Japan].

Abstract

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