Fluorine in medicine

H. Yamaguchi

doi:10.1039/9781839167591-00440

Fluorine in medicine

H. Yamaguchi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Abstract

In this chapter, the medical applications of fluorine atoms are discussed, focusing on ₁₈F-labelled positron emission tomography (PET) agents. Various drugs contain fluorine atoms, and recently fluorine has been used for in vivo imaging. Although ₁₉F magnetic resonance imaging via the stable ₁₉F isotope is still being researched, ₁₈F-PET imaging using radioactive ₁₈F is widely used in clinical examinations. Most of the 18F-PET agents used for such imaging are manufactured in hospitals using a cyclotron and labelling synthesizer, which is discussed along with the types of test agents available.

Original language	English
Title of host publication	Perfluoroalkyl Substances
Subtitle of host publication	Synthesis, Applications, Challenges and Regulations
Publisher	RSC
Pages	440-458
Number of pages	19
ISBN (Electronic)	9781839167591
ISBN (Print)	9781839165689
DOIs	https://doi.org/10.1039/9781839167591-00440
Publication status	Published - 15-08-2022
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Chemistry
General Environmental Science
General Energy
General Engineering

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10.1039/9781839167591-00440

Cite this

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abstract = "In this chapter, the medical applications of fluorine atoms are discussed, focusing on 18F-labelled positron emission tomography (PET) agents. Various drugs contain fluorine atoms, and recently fluorine has been used for in vivo imaging. Although 19F magnetic resonance imaging via the stable 19F isotope is still being researched, 18F-PET imaging using radioactive 18F is widely used in clinical examinations. Most of the 18F-PET agents used for such imaging are manufactured in hospitals using a cyclotron and labelling synthesizer, which is discussed along with the types of test agents available.",

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AB - In this chapter, the medical applications of fluorine atoms are discussed, focusing on 18F-labelled positron emission tomography (PET) agents. Various drugs contain fluorine atoms, and recently fluorine has been used for in vivo imaging. Although 19F magnetic resonance imaging via the stable 19F isotope is still being researched, 18F-PET imaging using radioactive 18F is widely used in clinical examinations. Most of the 18F-PET agents used for such imaging are manufactured in hospitals using a cyclotron and labelling synthesizer, which is discussed along with the types of test agents available.

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ER -

Fluorine in medicine

Abstract

All Science Journal Classification (ASJC) codes

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