Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection: A real-world perspective and review of the literature

Ahmed Babiker, Lloyd Clarke, Yohei Doi, Ryan K. Shields

Research output: Contribution to journalArticle

Abstract

Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87% and 94% at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings support fosfomycin treatment against MDR pathogens causing UTIs.

Original languageEnglish
Article number114856
JournalDiagnostic Microbiology and Infectious Disease
Volume95
Issue number3
DOIs
Publication statusPublished - 11-2019

Fingerprint

Fosfomycin
Urinary Tract Infections
Bacteria
Therapeutics

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

@article{d8a2682773fe4f90a8da28b9fdd88445,
title = "Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection: A real-world perspective and review of the literature",
abstract = "Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87{\%} and 94{\%} at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings support fosfomycin treatment against MDR pathogens causing UTIs.",
author = "Ahmed Babiker and Lloyd Clarke and Yohei Doi and Shields, {Ryan K.}",
year = "2019",
month = "11",
doi = "10.1016/j.diagmicrobio.2019.06.008",
language = "English",
volume = "95",
journal = "Diagnostic Microbiology and Infectious Disease",
issn = "0732-8893",
publisher = "Elsevier Inc.",
number = "3",

}

Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection : A real-world perspective and review of the literature. / Babiker, Ahmed; Clarke, Lloyd; Doi, Yohei; Shields, Ryan K.

In: Diagnostic Microbiology and Infectious Disease, Vol. 95, No. 3, 114856, 11.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Fosfomycin for treatment of multidrug-resistant pathogens causing urinary tract infection

T2 - A real-world perspective and review of the literature

AU - Babiker, Ahmed

AU - Clarke, Lloyd

AU - Doi, Yohei

AU - Shields, Ryan K.

PY - 2019/11

Y1 - 2019/11

N2 - Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87% and 94% at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings support fosfomycin treatment against MDR pathogens causing UTIs.

AB - Among 47 patients with urinary tract infections (UTIs) due to multidrug-resistant (MDR) bacteria, treatment with fosfomycin resulted in clinical cure rates of 87% and 94% at 48 hours and 14 days, respectively. Response rates did not vary across pathogens. Our retrospective, observational findings support fosfomycin treatment against MDR pathogens causing UTIs.

UR - http://www.scopus.com/inward/record.url?scp=85068776483&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85068776483&partnerID=8YFLogxK

U2 - 10.1016/j.diagmicrobio.2019.06.008

DO - 10.1016/j.diagmicrobio.2019.06.008

M3 - Article

AN - SCOPUS:85068776483

VL - 95

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

SN - 0732-8893

IS - 3

M1 - 114856

ER -