Foveal cone densitometry in high myopia

Naoichi Horio, Yozo Miyake, Masayuki Horiguchi

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4 Citations (Scopus)


We performed foveal cone densitometry using a modified fundus camera in 17 eyes of 17 normal subjects (age range, 20 to 47 yr, refractive error, + 2.0 to -2.5 D) and 15 eyes of 15 high myopia subjects with normal visual acuity (age range, 18 to 46 yr, refractive error, -9.0 to -14.5 D). After fully bleaching, the density of photopigment was measured for 7 minutes by a test spot of 562 nm in wavelength and 1 degree in diameter, focussed on the fovea. Two-way density and the time constant of pigment regeneration were calculated. No significant difference was found in two-way density between the two groups. The time constant in high myopia (161.6 ± 36.6 sec), however, was significantly increased (p<0.01), compared with normals (124.0±28.7 sec). To study the correlation of psychophysical visual function, we performed a photostress recovery test, which revealed a significant delay of the recovery time in high myopia (p<0.01). These results suggest that a delay in foveal cone pigment kinetics precedes loss of cone cells or chorioretinal degeneration in high myopia.

Original languageEnglish
Pages (from-to)235-239
Number of pages5
JournalJournal of Japanese Ophthalmological Society
Issue number3
Publication statusPublished - 03-1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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