TY - JOUR
T1 - Foveal thickness in occult macular dystrophy
AU - Kondo, Mineo
AU - Ito, Yasuki
AU - Ueno, Shinji
AU - Piao, Chang Hua
AU - Terasaki, Hiroko
AU - Miyake, Yozo
N1 - Funding Information:
Supported by the Grant-in Aid 13307048 (Y.M.), 14370557 (H.T.), 14770952 (M.K.) from the Ministry of Education, Science, Sports and Culture, Japan.
PY - 2003/5/1
Y1 - 2003/5/1
N2 - PURPOSE: Occult macular dystrophy (OMD) is an inherited macular dystrophy characterized by a progressive macular dysfunction without any visible fundus abnormality. We studied the foveal thickness in patients with OMD using optical coherence tomography (OCT). DESIGN: Observational case series. Foveal thickness by OCT images. METHODS: Foveal thickness obtained from 22 eyes of 11 patients with OMD was compared with that from 27 eyes of 20 age-matched normal controls. RESULTS: Mean foveal thickness in the patients group (96.5 ± 19.5 μm) was significantly thinner than that in the normal controls (133.3 ± 9.0 μm, P < .0001, Mann-Whitney U test). Eighteen of 22 eyes with OMD had foveal thickness that were thinner than the lower limit of the normal range. There was no statistically significant correlation between the foveal thickness and visual acuity, age, or duration from onset. CONCULUSION: These results demonstrated that there are significant anatomic changes in the macula of patients with OMD.
AB - PURPOSE: Occult macular dystrophy (OMD) is an inherited macular dystrophy characterized by a progressive macular dysfunction without any visible fundus abnormality. We studied the foveal thickness in patients with OMD using optical coherence tomography (OCT). DESIGN: Observational case series. Foveal thickness by OCT images. METHODS: Foveal thickness obtained from 22 eyes of 11 patients with OMD was compared with that from 27 eyes of 20 age-matched normal controls. RESULTS: Mean foveal thickness in the patients group (96.5 ± 19.5 μm) was significantly thinner than that in the normal controls (133.3 ± 9.0 μm, P < .0001, Mann-Whitney U test). Eighteen of 22 eyes with OMD had foveal thickness that were thinner than the lower limit of the normal range. There was no statistically significant correlation between the foveal thickness and visual acuity, age, or duration from onset. CONCULUSION: These results demonstrated that there are significant anatomic changes in the macula of patients with OMD.
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U2 - 10.1016/S0002-9394(02)02158-X
DO - 10.1016/S0002-9394(02)02158-X
M3 - Article
C2 - 12719092
AN - SCOPUS:0037404177
SN - 0002-9394
VL - 135
SP - 725
EP - 728
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 5
ER -