TY - JOUR
T1 - Fulminant Hepatitis in Primary Human Herpesvirus-6 Infection
AU - Sobue, Ryo
AU - Miyazaki, Hitoshi
AU - Okamoto, Masataka
AU - Hirano, Masami
AU - Yoshikawa, Tetsushi
AU - Suga, Sadao
AU - Asano, Yoshizo
PY - 1991/5/2
Y1 - 1991/5/2
N2 - To the Editor: Liver damage in primary human herpesvirus-6 infection has been reported in infants1,2 and adults.3 4 5 All patients had a benign, self-limited course except one infant with fatal fulminant hepatitis.1 We describe here an adult with fulminant hepatitis associated with lymphadenopathy and marked atypical lymphocytosis presumably caused by herpesvirus-6 infection. A 29-year-old man was admitted to our hospital on October 17, 1989, with fever, jaundice, skin rash, and lymphadenopathy, which had developed 10 days earlier. The bilirubin concentration (2.4 mg per deciliter), aminotransferase activities, and prothrombin time (18 percent) confirmed hepatic involvement. Generalized lymphadenopathy with leukocytosis (33,100 per.
AB - To the Editor: Liver damage in primary human herpesvirus-6 infection has been reported in infants1,2 and adults.3 4 5 All patients had a benign, self-limited course except one infant with fatal fulminant hepatitis.1 We describe here an adult with fulminant hepatitis associated with lymphadenopathy and marked atypical lymphocytosis presumably caused by herpesvirus-6 infection. A 29-year-old man was admitted to our hospital on October 17, 1989, with fever, jaundice, skin rash, and lymphadenopathy, which had developed 10 days earlier. The bilirubin concentration (2.4 mg per deciliter), aminotransferase activities, and prothrombin time (18 percent) confirmed hepatic involvement. Generalized lymphadenopathy with leukocytosis (33,100 per.
UR - https://www.scopus.com/pages/publications/0025819422
UR - https://www.scopus.com/pages/publications/0025819422#tab=citedBy
U2 - 10.1056/NEJM199105023241818
DO - 10.1056/NEJM199105023241818
M3 - Letter
C2 - 1849614
AN - SCOPUS:0025819422
SN - 0028-4793
VL - 324
SP - 1290
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 18
ER -
