TY - JOUR
T1 - Functional preservation in surgery for deep-seated meningiomas
AU - Hasegawa, Mitsuhiro
AU - Hayashi, Takuro
AU - Nagahisa, Shinya
AU - Adachi, Kazuhide
AU - Moriya, Shigeta
AU - Ganaha, Tsukasa
AU - Inamasu, Joji
AU - Hayakawa, Motoharu
AU - Hirose, Yuichi
N1 - Publisher Copyright:
© 2014, Japanese Congress of Neurological Surgeons. All rights reserved.
PY - 2014
Y1 - 2014
N2 - The functional prognosis for deep-seated meningiomas is mostly dictated by the approach chosen and the dissection technique employed to remove tumor tissue from deep veins, cranial nerves and the brainstem. Accordingly, in this study among a consecutive 293 meningioma operations, the incidence, location, preservation rate of cranial nerve function, and the most appropriate approach selection for deep-seated meningiomas were retrospectively analyzed. The rate of vision improvement was 89% in 36 cases with visual dysfunction, the olfaction preservation was 93% in 30 cases operated via a basal interhemispheric approach, and hearing rate improvement was 44% in 9 cases with hearing disturbances. In order to determine the most appropriate approach to gain direct observation and secure dissection, detailed neuro-imagings including 320-row area detector CT, preoperative embolization of feeders from the internal carotid artery, and a thorough understandings of the biological behavior and pathology of the tumor-brain interface are important. Finally, after due delligence, it may become apparent that a multi-staged operation and/or Simpson Grade IV surgery might be a good alternative choice.
AB - The functional prognosis for deep-seated meningiomas is mostly dictated by the approach chosen and the dissection technique employed to remove tumor tissue from deep veins, cranial nerves and the brainstem. Accordingly, in this study among a consecutive 293 meningioma operations, the incidence, location, preservation rate of cranial nerve function, and the most appropriate approach selection for deep-seated meningiomas were retrospectively analyzed. The rate of vision improvement was 89% in 36 cases with visual dysfunction, the olfaction preservation was 93% in 30 cases operated via a basal interhemispheric approach, and hearing rate improvement was 44% in 9 cases with hearing disturbances. In order to determine the most appropriate approach to gain direct observation and secure dissection, detailed neuro-imagings including 320-row area detector CT, preoperative embolization of feeders from the internal carotid artery, and a thorough understandings of the biological behavior and pathology of the tumor-brain interface are important. Finally, after due delligence, it may become apparent that a multi-staged operation and/or Simpson Grade IV surgery might be a good alternative choice.
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U2 - 10.7887/jcns.23.29
DO - 10.7887/jcns.23.29
M3 - Article
AN - SCOPUS:84923853495
SN - 0917-950X
VL - 23
SP - 29
EP - 36
JO - Japanese Journal of Neurosurgery
JF - Japanese Journal of Neurosurgery
IS - 1
ER -