Abstract
Identification of the genetic polymorphisms that contribute to susceptibility for schizophrenia have focused on the technique of genetic linkage, but now whole-genome association studies are becoming more feasible. Linkage analyses in families collected from different populations have provided relatively well-defined genomic loci. These have been typically followed by fine mapping studies using single nucleotide polymorphisms (SNPs). In this article, we review the current genetic evidence that implicates schizophrenia- susceptibility genes. Recently, it has been reported that more than 70% of genome regions are transcribed. From this point of view, the genetic study for identification of susceptive genes proceeds to another aspect of genome research.
Original language | English |
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Pages (from-to) | 131-134 |
Number of pages | 4 |
Journal | Japanese Journal of Neuropsychopharmacology |
Volume | 26 |
Issue number | 3 |
Publication status | Published - 01-06-2006 |
All Science Journal Classification (ASJC) codes
- Clinical Psychology
- Pharmacology
- Psychiatry and Mental health
- Pharmacology (medical)