TY - JOUR
T1 - Gastric Lesions in Rats Fed Salted Food Materials Commonly Eaten by Japanese
AU - Hirono, Iwao
AU - Funahashi, Masanori
AU - Kaneko, Chiyuki
AU - Ogino, Hiroshi
AU - Ito, Mitsuya
N1 - Funding Information:
The authors thank Dr. H. Takahashi of the Laboratory Animal Center, Fujita Health University, for valuable advice. This study was supported by a Grant-in-Aid from Fujita Health University. Address reprint requests to Dr. I. Hirono, Dept. of Pathology, Fujita Health University School of Medicine, Toyoake, Aichi 470-11, Japan. The present address of M. Funahashi is Dept. of Pathology, Fujita Health University School of Hygiene, Toyoake, Aichi 470-11, Japan. The present address of C. Kaneko is the Institute for Comprehensive Medical Science at the same university.
PY - 1990/1/1
Y1 - 1990/1/1
N2 - A high intake of salted food is thought to be related to the high incidence of stomach cancer in Japan. In the present study, female F344 rats were divided into four groups. They were fed a nutritionally deficient purified diet (Group 1) and standard purified diet (Group 3) for 113 weeks and the same diets supplemented with salted cuttlefish guts, broiled, salted, dried sardines, pickled radish, and soy sauce (Groups 2 and 4). The incidence of papillomas and ulcers of the forestomach was highest in Group 4, which was given the standard diet supplemented with the salty food materials (p & 0.05). These results suggest the importance of salted food as a suspicious causal factor in human stomach cancer in Japan.
AB - A high intake of salted food is thought to be related to the high incidence of stomach cancer in Japan. In the present study, female F344 rats were divided into four groups. They were fed a nutritionally deficient purified diet (Group 1) and standard purified diet (Group 3) for 113 weeks and the same diets supplemented with salted cuttlefish guts, broiled, salted, dried sardines, pickled radish, and soy sauce (Groups 2 and 4). The incidence of papillomas and ulcers of the forestomach was highest in Group 4, which was given the standard diet supplemented with the salty food materials (p & 0.05). These results suggest the importance of salted food as a suspicious causal factor in human stomach cancer in Japan.
UR - https://www.scopus.com/pages/publications/0025008047
UR - https://www.scopus.com/inward/citedby.url?scp=0025008047&partnerID=8YFLogxK
U2 - 10.1080/01635589009514086
DO - 10.1080/01635589009514086
M3 - Article
C2 - 2216897
AN - SCOPUS:0025008047
SN - 0163-5581
VL - 14
JO - Nutrition and Cancer
JF - Nutrition and Cancer
IS - 2
ER -
