TY - JOUR
T1 - GB virus C/hepatitis G virus infection among Colombian native Indians
AU - Tanaka, Yasuhito
AU - Mizokami, Masashi
AU - Orito, Etsuro
AU - Ohba, Ken Ichi
AU - Nakano, Tatsunori
AU - Kato, Takanobu
AU - Kondo, Yutaka
AU - Ding, Xin
AU - Ueda, Ryuzo
AU - Sonoda, Shunro
AU - Tajima, Kazuo
AU - Miura, Tomoyuki
AU - Hayami, Masanori
PY - 1998/9
Y1 - 1998/9
N2 - To elucidate the prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection in Colombian native Indians, serum GBV-C/HGV RNA was assayed in 163 native Indians and 67 members of the general population in Colombia. The native Indians (males:females = 40:123) and the members of the general population (males: females = 20:47) were tested by reverse transcription- semi-nested polymerase chain reaction. Of the 163 native Indians, 10 (6.1%) were positive for GBV-C/HGV RNA, compared with one (1.5%) of 67 from the general population. All Indians were negative for hepatitis B surface antigen and antibody to hepatitis C virus. Of 10 Indians with GBV-C/HGV RNA, the genotype of nine subjects was the Asian type. These data indicated that 1) the prevalence of GBV-C/HGV RNA in Colombian native Indians is high, and 2) GBV-C/HGV was probably brought from Asia and inherited for generations in some native Indian groups.
AB - To elucidate the prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection in Colombian native Indians, serum GBV-C/HGV RNA was assayed in 163 native Indians and 67 members of the general population in Colombia. The native Indians (males:females = 40:123) and the members of the general population (males: females = 20:47) were tested by reverse transcription- semi-nested polymerase chain reaction. Of the 163 native Indians, 10 (6.1%) were positive for GBV-C/HGV RNA, compared with one (1.5%) of 67 from the general population. All Indians were negative for hepatitis B surface antigen and antibody to hepatitis C virus. Of 10 Indians with GBV-C/HGV RNA, the genotype of nine subjects was the Asian type. These data indicated that 1) the prevalence of GBV-C/HGV RNA in Colombian native Indians is high, and 2) GBV-C/HGV was probably brought from Asia and inherited for generations in some native Indian groups.
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U2 - 10.4269/ajtmh.1998.59.462
DO - 10.4269/ajtmh.1998.59.462
M3 - Article
C2 - 9749645
AN - SCOPUS:17944400536
SN - 0002-9637
VL - 59
SP - 462
EP - 467
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 3
ER -
