GB virus C/hepatitis G virus infection in southern China

Rong Rong Wu; Masashi Mizokami; Kun Cao; Tatsunori Nakano; Xian Min Ge; Su Seng Wang; Etsuro Orito; Ken Ichi Ohba; Motokazu Mukaide; Kazumasa Hikiji; Johnson Y.N. Lau; Shiro Iino

doi:10.1093/infdis/175.1.168

GB virus C/hepatitis G virus infection in southern China

Rong Rong Wu, Masashi Mizokami, Kun Cao, Tatsunori Nakano, Xian Min Ge, Su Seng Wang, Etsuro Orito, Ken Ichi Ohba, Motokazu Mukaide, Kazumasa Hikiji, Johnson Y.N. Lau, Shiro Iino

Internal Medicine

Research output: Contribution to journal › Article › peer-review

63 Citations (Scopus)

Abstract

The prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among intravenous drug users (IVDUs), patients with liver diseases, and blood donors in Nanning, southern China was studied. GBV-C/HGV RNA was detected by reverse transcription polymerase chain reaction with primers derived from the 5'-untranslated region. GBV-C/HGV RNA was detected in 64 of 85 IVDUs, 20 of 80 persons with liver disease, and 1 of 50 blood donors. Among IVDUs, GBV- C/HGV infection was associated with antibodies to hepatitis C virus (HCV) and with hepatitis B surface antigen (HBsAg). Eleven nucleotide sequences were determined and analyzed by molecular evolutionary analysis. In a phylogenetic tree, the isolates were grouped in three clusters with GBV-C and HGV grouped in two clusters. These data indicate that GBV-C/HGV infection is common in China among IVDUs but uncommon among persons with liver disease without HBsAg or anti-HCV and that there is a new group of GBV-C/HGV.

Original language	English
Pages (from-to)	168-171
Number of pages	4
Journal	Journal of Infectious Diseases
Volume	175
Issue number	1
DOIs	https://doi.org/10.1093/infdis/175.1.168
Publication status	Published - 1997

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Infectious Diseases

Access to Document

10.1093/infdis/175.1.168

Fingerprint Dive into the research topics of 'GB virus C/hepatitis G virus infection in southern China'. Together they form a unique fingerprint.

Cite this

@article{79820184b10540f6bee999679e12d421,

title = "GB virus C/hepatitis G virus infection in southern China",

abstract = "The prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among intravenous drug users (IVDUs), patients with liver diseases, and blood donors in Nanning, southern China was studied. GBV-C/HGV RNA was detected by reverse transcription polymerase chain reaction with primers derived from the 5'-untranslated region. GBV-C/HGV RNA was detected in 64 of 85 IVDUs, 20 of 80 persons with liver disease, and 1 of 50 blood donors. Among IVDUs, GBV- C/HGV infection was associated with antibodies to hepatitis C virus (HCV) and with hepatitis B surface antigen (HBsAg). Eleven nucleotide sequences were determined and analyzed by molecular evolutionary analysis. In a phylogenetic tree, the isolates were grouped in three clusters with GBV-C and HGV grouped in two clusters. These data indicate that GBV-C/HGV infection is common in China among IVDUs but uncommon among persons with liver disease without HBsAg or anti-HCV and that there is a new group of GBV-C/HGV.",

author = "Wu, {Rong Rong} and Masashi Mizokami and Kun Cao and Tatsunori Nakano and Ge, {Xian Min} and Wang, {Su Seng} and Etsuro Orito and Ohba, {Ken Ichi} and Motokazu Mukaide and Kazumasa Hikiji and Lau, {Johnson Y.N.} and Shiro Iino",

year = "1997",

doi = "10.1093/infdis/175.1.168",

language = "English",

volume = "175",

pages = "168--171",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

publisher = "Oxford University Press",

number = "1",

}

GB virus C/hepatitis G virus infection in southern China. / Wu, Rong Rong; Mizokami, Masashi; Cao, Kun; Nakano, Tatsunori; Ge, Xian Min; Wang, Su Seng; Orito, Etsuro; Ohba, Ken Ichi; Mukaide, Motokazu; Hikiji, Kazumasa; Lau, Johnson Y.N.; Iino, Shiro.

In: Journal of Infectious Diseases, Vol. 175, No. 1, 1997, p. 168-171.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - GB virus C/hepatitis G virus infection in southern China

AU - Wu, Rong Rong

AU - Mizokami, Masashi

AU - Cao, Kun

AU - Nakano, Tatsunori

AU - Ge, Xian Min

AU - Wang, Su Seng

AU - Orito, Etsuro

AU - Ohba, Ken Ichi

AU - Mukaide, Motokazu

AU - Hikiji, Kazumasa

AU - Lau, Johnson Y.N.

AU - Iino, Shiro

PY - 1997

Y1 - 1997

N2 - The prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among intravenous drug users (IVDUs), patients with liver diseases, and blood donors in Nanning, southern China was studied. GBV-C/HGV RNA was detected by reverse transcription polymerase chain reaction with primers derived from the 5'-untranslated region. GBV-C/HGV RNA was detected in 64 of 85 IVDUs, 20 of 80 persons with liver disease, and 1 of 50 blood donors. Among IVDUs, GBV- C/HGV infection was associated with antibodies to hepatitis C virus (HCV) and with hepatitis B surface antigen (HBsAg). Eleven nucleotide sequences were determined and analyzed by molecular evolutionary analysis. In a phylogenetic tree, the isolates were grouped in three clusters with GBV-C and HGV grouped in two clusters. These data indicate that GBV-C/HGV infection is common in China among IVDUs but uncommon among persons with liver disease without HBsAg or anti-HCV and that there is a new group of GBV-C/HGV.

AB - The prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among intravenous drug users (IVDUs), patients with liver diseases, and blood donors in Nanning, southern China was studied. GBV-C/HGV RNA was detected by reverse transcription polymerase chain reaction with primers derived from the 5'-untranslated region. GBV-C/HGV RNA was detected in 64 of 85 IVDUs, 20 of 80 persons with liver disease, and 1 of 50 blood donors. Among IVDUs, GBV- C/HGV infection was associated with antibodies to hepatitis C virus (HCV) and with hepatitis B surface antigen (HBsAg). Eleven nucleotide sequences were determined and analyzed by molecular evolutionary analysis. In a phylogenetic tree, the isolates were grouped in three clusters with GBV-C and HGV grouped in two clusters. These data indicate that GBV-C/HGV infection is common in China among IVDUs but uncommon among persons with liver disease without HBsAg or anti-HCV and that there is a new group of GBV-C/HGV.

UR - http://www.scopus.com/inward/record.url?scp=16944364987&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=16944364987&partnerID=8YFLogxK

U2 - 10.1093/infdis/175.1.168

DO - 10.1093/infdis/175.1.168

M3 - Article

C2 - 8985213

AN - SCOPUS:16944364987

VL - 175

SP - 168

EP - 171

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 1

ER -