GB virus C/hepatitis G virus infection in southern China

Rong Rong Wu; Masashi Mizokami; Kun Cao; Tatsunori Nakano; Xian Min Ge; Su Seng Wang; Etsuro Orito; Ken Ichi Ohba; Motokazu Mukaide; Kazumasa Hikiji; Johnson Y.N. Lau; Shiro Iino

doi:10.1093/infdis/175.1.168

GB virus C/hepatitis G virus infection in southern China

Rong Rong Wu
, Masashi Mizokami
, Kun Cao
, Tatsunori Nakano
, Xian Min Ge
, Su Seng Wang
, Etsuro Orito
, Ken Ichi Ohba
, Motokazu Mukaide
, Kazumasa Hikiji
, Johnson Y.N. Lau
, Shiro Iino

Internal Medicine

Research output: Contribution to journal › Article › peer-review

69 Citations (Scopus)

Abstract

The prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among intravenous drug users (IVDUs), patients with liver diseases, and blood donors in Nanning, southern China was studied. GBV-C/HGV RNA was detected by reverse transcription polymerase chain reaction with primers derived from the 5'-untranslated region. GBV-C/HGV RNA was detected in 64 of 85 IVDUs, 20 of 80 persons with liver disease, and 1 of 50 blood donors. Among IVDUs, GBV- C/HGV infection was associated with antibodies to hepatitis C virus (HCV) and with hepatitis B surface antigen (HBsAg). Eleven nucleotide sequences were determined and analyzed by molecular evolutionary analysis. In a phylogenetic tree, the isolates were grouped in three clusters with GBV-C and HGV grouped in two clusters. These data indicate that GBV-C/HGV infection is common in China among IVDUs but uncommon among persons with liver disease without HBsAg or anti-HCV and that there is a new group of GBV-C/HGV.

Original language	English
Pages (from-to)	168-171
Number of pages	4
Journal	Journal of Infectious Diseases
Volume	175
Issue number	1
DOIs	https://doi.org/10.1093/infdis/175.1.168
Publication status	Published - 1997

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Infectious Diseases

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10.1093/infdis/175.1.168

Cite this

@article{79820184b10540f6bee999679e12d421,

title = "GB virus C/hepatitis G virus infection in southern China",

abstract = "The prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among intravenous drug users (IVDUs), patients with liver diseases, and blood donors in Nanning, southern China was studied. GBV-C/HGV RNA was detected by reverse transcription polymerase chain reaction with primers derived from the 5'-untranslated region. GBV-C/HGV RNA was detected in 64 of 85 IVDUs, 20 of 80 persons with liver disease, and 1 of 50 blood donors. Among IVDUs, GBV- C/HGV infection was associated with antibodies to hepatitis C virus (HCV) and with hepatitis B surface antigen (HBsAg). Eleven nucleotide sequences were determined and analyzed by molecular evolutionary analysis. In a phylogenetic tree, the isolates were grouped in three clusters with GBV-C and HGV grouped in two clusters. These data indicate that GBV-C/HGV infection is common in China among IVDUs but uncommon among persons with liver disease without HBsAg or anti-HCV and that there is a new group of GBV-C/HGV.",

author = "Wu, \{Rong Rong\} and Masashi Mizokami and Kun Cao and Tatsunori Nakano and Ge, \{Xian Min\} and Wang, \{Su Seng\} and Etsuro Orito and Ohba, \{Ken Ichi\} and Motokazu Mukaide and Kazumasa Hikiji and Lau, \{Johnson Y.N.\} and Shiro Iino",

year = "1997",

doi = "10.1093/infdis/175.1.168",

language = "English",

volume = "175",

pages = "168--171",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

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T1 - GB virus C/hepatitis G virus infection in southern China

AU - Wu, Rong Rong

AU - Mizokami, Masashi

AU - Cao, Kun

AU - Nakano, Tatsunori

AU - Ge, Xian Min

AU - Wang, Su Seng

AU - Orito, Etsuro

AU - Ohba, Ken Ichi

AU - Mukaide, Motokazu

AU - Hikiji, Kazumasa

AU - Lau, Johnson Y.N.

AU - Iino, Shiro

PY - 1997

Y1 - 1997

N2 - The prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among intravenous drug users (IVDUs), patients with liver diseases, and blood donors in Nanning, southern China was studied. GBV-C/HGV RNA was detected by reverse transcription polymerase chain reaction with primers derived from the 5'-untranslated region. GBV-C/HGV RNA was detected in 64 of 85 IVDUs, 20 of 80 persons with liver disease, and 1 of 50 blood donors. Among IVDUs, GBV- C/HGV infection was associated with antibodies to hepatitis C virus (HCV) and with hepatitis B surface antigen (HBsAg). Eleven nucleotide sequences were determined and analyzed by molecular evolutionary analysis. In a phylogenetic tree, the isolates were grouped in three clusters with GBV-C and HGV grouped in two clusters. These data indicate that GBV-C/HGV infection is common in China among IVDUs but uncommon among persons with liver disease without HBsAg or anti-HCV and that there is a new group of GBV-C/HGV.

AB - The prevalence of GB virus C/hepatitis G virus (GBV-C/HGV) infection among intravenous drug users (IVDUs), patients with liver diseases, and blood donors in Nanning, southern China was studied. GBV-C/HGV RNA was detected by reverse transcription polymerase chain reaction with primers derived from the 5'-untranslated region. GBV-C/HGV RNA was detected in 64 of 85 IVDUs, 20 of 80 persons with liver disease, and 1 of 50 blood donors. Among IVDUs, GBV- C/HGV infection was associated with antibodies to hepatitis C virus (HCV) and with hepatitis B surface antigen (HBsAg). Eleven nucleotide sequences were determined and analyzed by molecular evolutionary analysis. In a phylogenetic tree, the isolates were grouped in three clusters with GBV-C and HGV grouped in two clusters. These data indicate that GBV-C/HGV infection is common in China among IVDUs but uncommon among persons with liver disease without HBsAg or anti-HCV and that there is a new group of GBV-C/HGV.

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DO - 10.1093/infdis/175.1.168

M3 - Article

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AN - SCOPUS:16944364987

SN - 0022-1899

VL - 175

SP - 168

EP - 171

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

IS - 1

ER -

GB virus C/hepatitis G virus infection in southern China

Abstract

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