Generation of a control human induced pluripotent stem cell line using the defective and persistent Sendai virus vector system

  • Zhi Zhou
  • , Sho Yoshimatsu
  • , Emi Qian
  • , Mitsuru Ishikawa
  • , Tsukika Sato
  • , Manami Ohtaka
  • , Mahito Nakanishi
  • , Hideyuki Okano

Research output: Contribution to journalArticlepeer-review

Abstract

The defective and persistent Sendai virus (SeVdp) vector system allows efficient generation of transgene-free induced pluripotent stem cells (iPSCs) from human somatic cells. By leveraging the system, here we report the generation of an iPSC line from somatic fibroblasts of a healthy control donner (female), named KEIOi002-A (also named YG-iPS). The control iPSC line would be a useful resource for stem cell research and regenerative medicine.

Original languageEnglish
Article number102549
JournalStem Cell Research
Volume56
DOIs
Publication statusPublished - 10-2021
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

  • Developmental Biology
  • Cell Biology

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