Genetic variation affects de novo translocation frequency

Takema Kato; Hidehito Inagaki; Kouji Yamada; Hiroshi Kogo; Tamae Ohye; Hiroe Kowa; Kayuri Nagaoka; Mariko Taniguchi; Beverly S. Emanuel; Hiroki Kurahashi

doi:10.1126/science.1121452

Genetic variation affects de novo translocation frequency

Takema Kato, Hidehito Inagaki, Kouji Yamada, Hiroshi Kogo, Tamae Ohye, Hiroe Kowa, Kayuri Nagaoka, Mariko Taniguchi, Beverly S. Emanuel, Hiroki Kurahashi

Division of Molecular Genetics

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

Abstract

A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.

Original language	English
Pages (from-to)	971
Number of pages	1
Journal	Science
Volume	311
Issue number	5763
DOIs	https://doi.org/10.1126/science.1121452
Publication status	Published - 17-02-2006

All Science Journal Classification (ASJC) codes

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@article{b3c68334c4494fc08409c2f2ffd397d7,

title = "Genetic variation affects de novo translocation frequency",

abstract = "A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.",

author = "Takema Kato and Hidehito Inagaki and Kouji Yamada and Hiroshi Kogo and Tamae Ohye and Hiroe Kowa and Kayuri Nagaoka and Mariko Taniguchi and Emanuel, {Beverly S.} and Hiroki Kurahashi",

year = "2006",

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doi = "10.1126/science.1121452",

language = "English",

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journal = "Science",

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publisher = "American Association for the Advancement of Science",

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T1 - Genetic variation affects de novo translocation frequency

AU - Kato, Takema

AU - Inagaki, Hidehito

AU - Yamada, Kouji

AU - Kogo, Hiroshi

AU - Ohye, Tamae

AU - Kowa, Hiroe

AU - Nagaoka, Kayuri

AU - Taniguchi, Mariko

AU - Emanuel, Beverly S.

AU - Kurahashi, Hiroki

PY - 2006/2/17

Y1 - 2006/2/17

N2 - A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.

AB - A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.

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UR - http://www.scopus.com/inward/citedby.url?scp=33144472660&partnerID=8YFLogxK

U2 - 10.1126/science.1121452

DO - 10.1126/science.1121452

M3 - Article

C2 - 16484486

AN - SCOPUS:33144472660

SN - 0036-8075

VL - 311

SP - 971

JO - Science

JF - Science

IS - 5763

ER -

Genetic variation affects de novo translocation frequency

Abstract

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