Genetic variation affects de novo translocation frequency

Takema Kato; Hidehito Inagaki; Kouji Yamada; Hiroshi Kogo; Tamae Ohye; Hiroe Kowa; Kayuri Nagaoka; Mariko Taniguchi; Beverly S. Emanuel; Hiroki Kurahashi

doi:10.1126/science.1121452

Genetic variation affects de novo translocation frequency

Takema Kato
, Hidehito Inagaki
, Kouji Yamada
, Hiroshi Kogo
, Tamae Ohye
, Hiroe Kowa
, Kayuri Nagaoka
, Mariko Taniguchi
, Beverly S. Emanuel
, Hiroki Kurahashi

Division of Molecular Genetics

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Abstract

A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.

Original language	English
Pages (from-to)	971
Number of pages	1
Journal	Science
Volume	311
Issue number	5763
DOIs	https://doi.org/10.1126/science.1121452
Publication status	Published - 17-02-2006

All Science Journal Classification (ASJC) codes

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10.1126/science.1121452

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@article{b3c68334c4494fc08409c2f2ffd397d7,

title = "Genetic variation affects de novo translocation frequency",

abstract = "A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.",

author = "Takema Kato and Hidehito Inagaki and Kouji Yamada and Hiroshi Kogo and Tamae Ohye and Hiroe Kowa and Kayuri Nagaoka and Mariko Taniguchi and Emanuel, \{Beverly S.\} and Hiroki Kurahashi",

year = "2006",

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day = "17",

doi = "10.1126/science.1121452",

language = "English",

volume = "311",

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journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

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TY - JOUR

T1 - Genetic variation affects de novo translocation frequency

AU - Kato, Takema

AU - Inagaki, Hidehito

AU - Yamada, Kouji

AU - Kogo, Hiroshi

AU - Ohye, Tamae

AU - Kowa, Hiroe

AU - Nagaoka, Kayuri

AU - Taniguchi, Mariko

AU - Emanuel, Beverly S.

AU - Kurahashi, Hiroki

PY - 2006/2/17

Y1 - 2006/2/17

N2 - A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.

AB - A palindromic sequence on human chromosome 11 causes frequent translocations during meiosis, while a more recently evolved nonpalindromic allele does not.

UR - https://www.scopus.com/pages/publications/33144472660

UR - https://www.scopus.com/pages/publications/33144472660#tab=citedBy

U2 - 10.1126/science.1121452

DO - 10.1126/science.1121452

M3 - Article

C2 - 16484486

AN - SCOPUS:33144472660

SN - 0036-8075

VL - 311

SP - 971

JO - Science

JF - Science

IS - 5763

ER -

Genetic variation affects de novo translocation frequency

Abstract

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