TY - JOUR
T1 - Genomic characterization of a novel G3P[10] rotavirus strain from a diarrheic child in Thailand
T2 - Evidence for bat-to-human zoonotic transmission
AU - Komoto, Satoshi
AU - Tacharoenmuang, Ratana
AU - Guntapong, Ratigorn
AU - Upachai, Sompong
AU - Singchai, Phakapun
AU - Ide, Tomihiko
AU - Fukuda, Saori
AU - Hatazawa, Riona
AU - Sutthiwarakom, Karun
AU - Kongjorn, Santip
AU - Onvimala, Napa
AU - Luechakham, Tipsuda
AU - Sriwanthana, Busarawan
AU - Murata, Takayuki
AU - Uppapong, Ballang
AU - Taniguchi, Koki
N1 - Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2021/1
Y1 - 2021/1
N2 - An unusual rotavirus strain with the G3P[10] genotype (RVA/Human-wt/THA/MS2015-1-0001/2015/G3P[10]) was identified in a stool sample from a hospitalized child aged 11 months with severe gastroenteritis in Thailand. In the current study, we sequenced and characterized the full genome of strain MS2015-1-0001. On full-genomic analysis, strain MS2015-1-0001 exhibited the following genotype configuration: G3-P[10]-I8-R3-C3-M3-A9-N3-T3-E3-H6, which is identical or closely related to those of bat and bat-like rotavirus strains (MYAS33-like). Furthermore, phylogenetic analysis revealed that all 11 genes of strain MS2015-1-0001 appeared to be of bat origin. Our findings provide evidence for bat-to-human interspecies transmission of rotaviruses and important insights into dynamic interactions between human and bat rotavirus strains.
AB - An unusual rotavirus strain with the G3P[10] genotype (RVA/Human-wt/THA/MS2015-1-0001/2015/G3P[10]) was identified in a stool sample from a hospitalized child aged 11 months with severe gastroenteritis in Thailand. In the current study, we sequenced and characterized the full genome of strain MS2015-1-0001. On full-genomic analysis, strain MS2015-1-0001 exhibited the following genotype configuration: G3-P[10]-I8-R3-C3-M3-A9-N3-T3-E3-H6, which is identical or closely related to those of bat and bat-like rotavirus strains (MYAS33-like). Furthermore, phylogenetic analysis revealed that all 11 genes of strain MS2015-1-0001 appeared to be of bat origin. Our findings provide evidence for bat-to-human interspecies transmission of rotaviruses and important insights into dynamic interactions between human and bat rotavirus strains.
UR - https://www.scopus.com/pages/publications/85097582623
UR - https://www.scopus.com/pages/publications/85097582623#tab=citedBy
U2 - 10.1016/j.meegid.2020.104667
DO - 10.1016/j.meegid.2020.104667
M3 - Article
C2 - 33285275
AN - SCOPUS:85097582623
SN - 1567-1348
VL - 87
JO - Infection, Genetics and Evolution
JF - Infection, Genetics and Evolution
M1 - 104667
ER -
