TY - JOUR
T1 - Genotype announcement to Japanese smokers who attended a health checkup examination
AU - Hamajima, Nobuyuki
AU - Suzuki, Koji
AU - Ito, Yoshinori
AU - Kondo, Takaaki
PY - 2005/12/20
Y1 - 2005/12/20
N2 - Background: Genotype announcement may be one of the effective methods to induce smoking cessation, but the studies are limited throughout the world. Methods: Subjects were smokers who attended a health checkup examination provided by a local government in Hokkaido, Japan, 2003. Those who agreed to know their genotypes were informed of the genotypes of glutathione S-transferease (GST) M1 present/null, GSTT1 present/null, and NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T (Pro187Ser). Results: Out of 143 smokers (92 males and 51 females), 101 individuals participated in the present study. A postal questionnaire one year after the genotype announcement found that 8 persons (6 males and 2 females) of 41 respondents had quitted smoking. Two of 8 quitters stated that they had quitted smoking due to the announcement. There were none who regretted the genotype tests. Conclution: Although the cessation rate, 7.9% (8/101) at least, was not marked, no harmful effects were observed among the respondents.
AB - Background: Genotype announcement may be one of the effective methods to induce smoking cessation, but the studies are limited throughout the world. Methods: Subjects were smokers who attended a health checkup examination provided by a local government in Hokkaido, Japan, 2003. Those who agreed to know their genotypes were informed of the genotypes of glutathione S-transferease (GST) M1 present/null, GSTT1 present/null, and NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T (Pro187Ser). Results: Out of 143 smokers (92 males and 51 females), 101 individuals participated in the present study. A postal questionnaire one year after the genotype announcement found that 8 persons (6 males and 2 females) of 41 respondents had quitted smoking. Two of 8 quitters stated that they had quitted smoking due to the announcement. There were none who regretted the genotype tests. Conclution: Although the cessation rate, 7.9% (8/101) at least, was not marked, no harmful effects were observed among the respondents.
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U2 - 10.2188/jea.16.45
DO - 10.2188/jea.16.45
M3 - Article
C2 - 16369108
AN - SCOPUS:30344447541
SN - 0917-5040
VL - 16
SP - 45
EP - 47
JO - Journal of epidemiology
JF - Journal of epidemiology
IS - 1
ER -