Abstract
Chemical constituents as well as cytotoxic and insecticidal activity of the crude methanol extract from the leaves of Phyllanthus reticulatus Poir. (Euphorbiaceae) were investigated. (5R*,6R*)-4,6-Dimethoxycarbonyl- 5-[2′,3′,4′-trihydroxy-6′-(methoxycarbonyl) phenyl]-5,6-dihydro-2H-pyran-2-one (1) along with 3,4,3′-tri-O- methylellagic acid, and methyl gallate were isolated from the dichloromethane extract. Determination of their structures was based on spectroscopic analysis. Compound 1 possessed a very weak insecticidal activity against Spodoptera frugiperda (Sf9) with an IC 50 value of 27.27μg/mL.
| Original language | English |
|---|---|
| Pages (from-to) | 740-744 |
| Number of pages | 5 |
| Journal | Pharmaceutical Biology |
| Volume | 48 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 07-2010 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
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