Glioblastoma multiforme in the left frontal lobe subsequent to malignant lymphoma in the right orbit

Mamoru Tomida, Masaaki Muraki, Hisaya Hiramatsu, Katsuyuki Tsukamoto, Kaoru Hinokuma, Kenichi Uemura, Atsuo Masago, Yukihiko Ueda, Hideo Mabe, Makoto Kuroda, Takaaki Nakamura

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2 Citations (Scopus)


A 62-year-old male presented with glioblastoma multiforme in the left frontal lobe manifesting as motor aphasia, subsequent to a malignant lymphoma in the right orbit. He underwent subtotal removal of the right orbital mass presenting as right exophthalmos which was shown by histological examination to be non-Hodgkin's lymphoma. He received 30 Gy Lineac irradiation to the right orbit. His post-operative course was satisfactory. Magnetic resonance (MR) imaging with gadolinium-diethylenetriaminepenta-acetic acid (Gd-DTPA) 7 months later demonstrated a small spotty enhanced lesion in the left frontal lobe. He developed motor aphasia 1 year after irradiation. MR imaging disclosed an enhanced mass in the left frontal lobe, which was totally removed. Histological examination revealed glioblastoma multiforme. Patients with malignant lymphoma may develop a subsequent second malignant tumor. MR imaging with Gd-DTPA is quite useful for early detection of a second brain tumor.

Original languageEnglish
Pages (from-to)11-14
Number of pages4
Journalneurologia medico-chirurgica
Issue number1
Publication statusPublished - 01-1996

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


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