Global implementation of genomic medicine: We are not alone

Teri A. Manolio; Marc Abramowicz; Fahd Al-Mulla; Warwick Anderson; Rudi Balling; Adam C. Berger; Steven Bleyl; Aravinda Chakravarti; Wasun Chantratita; Rex L. Chisholm; Vajira H.W. Dissanayake; Michael Dunn; Victor J. Dzau; Bok Ghee Han; Tim Hubbard; Anne Kolbe; Bruce Korf; Michiaki Kubo; Paul Lasko; Erkki Leego; Surakameth Mahasirimongkol; Partha P. Majumdar; Gert Matthijs; Howard L. McLeod; Andres Metspalu; Pierre Meulien; Satoru Miyano; Yaakov Naparstek; P. Pearl O'Rourke; George P. Patrinos; Heidi L. Rehm; Mary V. Relling; Gad Rennert; Laura Lyman Rodriguez; Dan M. Roden; Alan R. Shuldiner; Sukdeb Sinha; Patrick Tan; Mats Ulfendahl; Robyn Ward; Marc S. Williams; John E.L. Wong; Eric D. Green; Geofrey S. Ginsburg

doi:10.1126/scitranslmed.aab0194

Global implementation of genomic medicine: We are not alone

Teri A. Manolio, Marc Abramowicz, Fahd Al-Mulla, Warwick Anderson, Rudi Balling, Adam C. Berger, Steven Bleyl, Aravinda Chakravarti, Wasun Chantratita, Rex L. Chisholm, Vajira H.W. Dissanayake, Michael Dunn, Victor J. Dzau, Bok Ghee Han, Tim Hubbard, Anne Kolbe, Bruce Korf, Michiaki Kubo, Paul Lasko, Erkki LeegoSurakameth Mahasirimongkol, Partha P. Majumdar, Gert Matthijs, Howard L. McLeod, Andres Metspalu, Pierre Meulien, Satoru Miyano, Yaakov Naparstek, P. Pearl O'Rourke, George P. Patrinos, Heidi L. Rehm, Mary V. Relling, Gad Rennert, Laura Lyman Rodriguez, Dan M. Roden, Alan R. Shuldiner, Sukdeb Sinha, Patrick Tan, Mats Ulfendahl, Robyn Ward, Marc S. Williams, John E.L. Wong, Eric D. Green, Geofrey S. Ginsburg

Research output: Contribution to journal › Review article › peer-review

156 Citations (Scopus)

Abstract

Around the world, innovative genomic-medicine programs capitalize on singular capabilities arising from local health care systems, cultural or political milieus, and unusual selected risk alleles or disease burdens. Such individual eforts might beneft from the sharing of approaches and lessons learned in other locales. The U.S. National Human Genome Research Institute and the National Academy of Medicine recently brought together 25 of these groups to compare projects, to examine the current state of implementation and desired near-term capabilities, and to identify opportunities for collaboration that promote the responsible practice of genomic medicine. Eforts to coalesce these groups around concrete but compelling signature projects should accelerate the responsible implementation of genomic medicine in eforts to improve clinical care worldwide.

Original language	English
Article number	290ps13
Journal	Science Translational Medicine
Volume	7
Issue number	290
DOIs	https://doi.org/10.1126/scitranslmed.aab0194
Publication status	Published - 03-06-2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1126/scitranslmed.aab0194

Cite this

Manolio, T. A., Abramowicz, M., Al-Mulla, F., Anderson, W., Balling, R., Berger, A. C., Bleyl, S., Chakravarti, A., Chantratita, W., Chisholm, R. L., Dissanayake, V. H. W., Dunn, M., Dzau, V. J., Han, B. G., Hubbard, T., Kolbe, A., Korf, B., Kubo, M., Lasko, P., ... Ginsburg, G. S. (2015). Global implementation of genomic medicine: We are not alone. Science Translational Medicine, 7(290), Article 290ps13. https://doi.org/10.1126/scitranslmed.aab0194

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title = "Global implementation of genomic medicine: We are not alone",

abstract = "Around the world, innovative genomic-medicine programs capitalize on singular capabilities arising from local health care systems, cultural or political milieus, and unusual selected risk alleles or disease burdens. Such individual eforts might beneft from the sharing of approaches and lessons learned in other locales. The U.S. National Human Genome Research Institute and the National Academy of Medicine recently brought together 25 of these groups to compare projects, to examine the current state of implementation and desired near-term capabilities, and to identify opportunities for collaboration that promote the responsible practice of genomic medicine. Eforts to coalesce these groups around concrete but compelling signature projects should accelerate the responsible implementation of genomic medicine in eforts to improve clinical care worldwide.",

author = "Manolio, {Teri A.} and Marc Abramowicz and Fahd Al-Mulla and Warwick Anderson and Rudi Balling and Berger, {Adam C.} and Steven Bleyl and Aravinda Chakravarti and Wasun Chantratita and Chisholm, {Rex L.} and Dissanayake, {Vajira H.W.} and Michael Dunn and Dzau, {Victor J.} and Han, {Bok Ghee} and Tim Hubbard and Anne Kolbe and Bruce Korf and Michiaki Kubo and Paul Lasko and Erkki Leego and Surakameth Mahasirimongkol and Majumdar, {Partha P.} and Gert Matthijs and McLeod, {Howard L.} and Andres Metspalu and Pierre Meulien and Satoru Miyano and Yaakov Naparstek and O'Rourke, {P. Pearl} and Patrinos, {George P.} and Rehm, {Heidi L.} and Relling, {Mary V.} and Gad Rennert and Rodriguez, {Laura Lyman} and Roden, {Dan M.} and Shuldiner, {Alan R.} and Sukdeb Sinha and Patrick Tan and Mats Ulfendahl and Robyn Ward and Williams, {Marc S.} and Wong, {John E.L.} and Green, {Eric D.} and Ginsburg, {Geofrey S.}",

year = "2015",

month = jun,

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doi = "10.1126/scitranslmed.aab0194",

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Manolio, TA, Abramowicz, M, Al-Mulla, F, Anderson, W, Balling, R, Berger, AC, Bleyl, S, Chakravarti, A, Chantratita, W, Chisholm, RL, Dissanayake, VHW, Dunn, M, Dzau, VJ, Han, BG, Hubbard, T, Kolbe, A, Korf, B, Kubo, M, Lasko, P, Leego, E, Mahasirimongkol, S, Majumdar, PP, Matthijs, G, McLeod, HL, Metspalu, A, Meulien, P, Miyano, S, Naparstek, Y, O'Rourke, PP, Patrinos, GP, Rehm, HL, Relling, MV, Rennert, G, Rodriguez, LL, Roden, DM, Shuldiner, AR, Sinha, S, Tan, P, Ulfendahl, M, Ward, R, Williams, MS, Wong, JEL, Green, ED & Ginsburg, GS 2015, 'Global implementation of genomic medicine: We are not alone', Science Translational Medicine, vol. 7, no. 290, 290ps13. https://doi.org/10.1126/scitranslmed.aab0194

TY - JOUR

T1 - Global implementation of genomic medicine

T2 - We are not alone

AU - Manolio, Teri A.

AU - Abramowicz, Marc

AU - Al-Mulla, Fahd

AU - Anderson, Warwick

AU - Balling, Rudi

AU - Berger, Adam C.

AU - Bleyl, Steven

AU - Chakravarti, Aravinda

AU - Chantratita, Wasun

AU - Chisholm, Rex L.

AU - Dissanayake, Vajira H.W.

AU - Dunn, Michael

AU - Dzau, Victor J.

AU - Han, Bok Ghee

AU - Hubbard, Tim

AU - Kolbe, Anne

AU - Korf, Bruce

AU - Kubo, Michiaki

AU - Lasko, Paul

AU - Leego, Erkki

AU - Mahasirimongkol, Surakameth

AU - Majumdar, Partha P.

AU - Matthijs, Gert

AU - McLeod, Howard L.

AU - Metspalu, Andres

AU - Meulien, Pierre

AU - Miyano, Satoru

AU - Naparstek, Yaakov

AU - O'Rourke, P. Pearl

AU - Patrinos, George P.

AU - Rehm, Heidi L.

AU - Relling, Mary V.

AU - Rennert, Gad

AU - Rodriguez, Laura Lyman

AU - Roden, Dan M.

AU - Shuldiner, Alan R.

AU - Sinha, Sukdeb

AU - Tan, Patrick

AU - Ulfendahl, Mats

AU - Ward, Robyn

AU - Williams, Marc S.

AU - Wong, John E.L.

AU - Green, Eric D.

AU - Ginsburg, Geofrey S.

PY - 2015/6/3

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AB - Around the world, innovative genomic-medicine programs capitalize on singular capabilities arising from local health care systems, cultural or political milieus, and unusual selected risk alleles or disease burdens. Such individual eforts might beneft from the sharing of approaches and lessons learned in other locales. The U.S. National Human Genome Research Institute and the National Academy of Medicine recently brought together 25 of these groups to compare projects, to examine the current state of implementation and desired near-term capabilities, and to identify opportunities for collaboration that promote the responsible practice of genomic medicine. Eforts to coalesce these groups around concrete but compelling signature projects should accelerate the responsible implementation of genomic medicine in eforts to improve clinical care worldwide.

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U2 - 10.1126/scitranslmed.aab0194

DO - 10.1126/scitranslmed.aab0194

M3 - Review article

C2 - 26041702

AN - SCOPUS:84930433702

SN - 1946-6234

VL - 7

JO - Science Translational Medicine

JF - Science Translational Medicine

IS - 290

M1 - 290ps13

ER -

Global implementation of genomic medicine: We are not alone

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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