Global implementation of genomic medicine: We are not alone

Teri A. Manolio, Marc Abramowicz, Fahd Al-Mulla, Warwick Anderson, Rudi Balling, Adam C. Berger, Steven Bleyl, Aravinda Chakravarti, Wasun Chantratita, Rex L. Chisholm, Vajira H.W. Dissanayake, Michael Dunn, Victor J. Dzau, Bok Ghee Han, Tim Hubbard, Anne Kolbe, Bruce Korf, Michiaki Kubo, Paul Lasko, Erkki LeegoSurakameth Mahasirimongkol, Partha P. Majumdar, Gert Matthijs, Howard L. McLeod, Andres Metspalu, Pierre Meulien, Satoru Miyano, Yaakov Naparstek, P. Pearl O'Rourke, George P. Patrinos, Heidi L. Rehm, Mary V. Relling, Gad Rennert, Laura Lyman Rodriguez, Dan M. Roden, Alan R. Shuldiner, Sukdeb Sinha, Patrick Tan, Mats Ulfendahl, Robyn Ward, Marc S. Williams, John E.L. Wong, Eric D. Green, Geofrey S. Ginsburg

Research output: Contribution to journalReview article

85 Citations (Scopus)

Abstract

Around the world, innovative genomic-medicine programs capitalize on singular capabilities arising from local health care systems, cultural or political milieus, and unusual selected risk alleles or disease burdens. Such individual eforts might beneft from the sharing of approaches and lessons learned in other locales. The U.S. National Human Genome Research Institute and the National Academy of Medicine recently brought together 25 of these groups to compare projects, to examine the current state of implementation and desired near-term capabilities, and to identify opportunities for collaboration that promote the responsible practice of genomic medicine. Eforts to coalesce these groups around concrete but compelling signature projects should accelerate the responsible implementation of genomic medicine in eforts to improve clinical care worldwide.

Original languageEnglish
Article number290ps13
JournalScience Translational Medicine
Volume7
Issue number290
DOIs
Publication statusPublished - 03-06-2015

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Manolio, T. A., Abramowicz, M., Al-Mulla, F., Anderson, W., Balling, R., Berger, A. C., Bleyl, S., Chakravarti, A., Chantratita, W., Chisholm, R. L., Dissanayake, V. H. W., Dunn, M., Dzau, V. J., Han, B. G., Hubbard, T., Kolbe, A., Korf, B., Kubo, M., Lasko, P., ... Ginsburg, G. S. (2015). Global implementation of genomic medicine: We are not alone. Science Translational Medicine, 7(290), [290ps13]. https://doi.org/10.1126/scitranslmed.aab0194