Gorham-Stout Disease Resulting in Spinal Deformity Treated by Fusion Surgery Combined With Everolimus Therapy: A Case Report

Akira Toga, Kota Watanabe, Satoshi Suzuki, Satoshi Nori, Osahiko Tsuji, Narihito Nagoshi, Eijiro Okada, Mitsuru Yagi, Nobuyuki Fujita, Masaya Nakamura, Morio Matsumoto

Research output: Contribution to journalArticlepeer-review

Abstract

CASE: Gorham-Stout disease (GSD) is a rare disorder characterized by progressive localized osteolysis and lymphatic malformation. A 26-year-old woman with GSD presented to our hospital with a Cobb angle of 100° and a kyphosis angle of 88°. Everolimus therapy was initiated to control the disease prior to surgery. After halo-gravity traction for 4 weeks, we performed anterior and posterior spinal fusion. Postoperative computed tomography revealed satisfactory bone union and no significant loss of correction 1 year post-surgery. CONCLUSION: This case suggests that anterior and posterior spinal fusion combined with everolimus therapy can be a therapeutic option for GSD.

Original languageEnglish
JournalJBJS Case Connector
Volume11
Issue number1
Publication statusPublished - 03-03-2021

All Science Journal Classification (ASJC) codes

  • Surgery
  • Orthopedics and Sports Medicine

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