Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

Hiroshi Oiwa; Keichiro Mihara; Takanobu Kan; Maiko Tanaka; Hajime Shindo; Kazuhiko Kumagai; Eiji Sugiyama

doi:10.2169/internalmedicine.53.2593

Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

Hiroshi Oiwa, Keichiro Mihara, Takanobu Kan, Maiko Tanaka, Hajime Shindo, Kazuhiko Kumagai, Eiji Sugiyama

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.

Original language	English
Pages (from-to)	1873-1875
Number of pages	3
Journal	Internal Medicine
Volume	53
Issue number	16
DOIs	https://doi.org/10.2169/internalmedicine.53.2593
Publication status	Published - 2014
Externally published	Yes

All Science Journal Classification (ASJC) codes

Internal Medicine

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10.2169/internalmedicine.53.2593

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title = "Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis",

abstract = "Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.",

author = "Hiroshi Oiwa and Keichiro Mihara and Takanobu Kan and Maiko Tanaka and Hajime Shindo and Kazuhiko Kumagai and Eiji Sugiyama",

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language = "English",

volume = "53",

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T1 - Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

AU - Oiwa, Hiroshi

AU - Mihara, Keichiro

AU - Kan, Takanobu

AU - Tanaka, Maiko

AU - Shindo, Hajime

AU - Kumagai, Kazuhiko

AU - Sugiyama, Eiji

PY - 2014

Y1 - 2014

N2 - Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.

AB - Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.

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U2 - 10.2169/internalmedicine.53.2593

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AN - SCOPUS:84906771303

SN - 0918-2918

VL - 53

SP - 1873

EP - 1875

JO - Internal Medicine

JF - Internal Medicine

IS - 16

ER -

Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

Abstract

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