Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

Hiroshi Oiwa, Keichiro Mihara, Takanobu Kan, Maiko Tanaka, Hajime Shindo, Kazuhiko Kumagai, Eiji Sugiyama

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.

Original languageEnglish
Pages (from-to)1873-1875
Number of pages3
JournalInternal Medicine
Volume53
Issue number16
DOIs
Publication statusPublished - 01-01-2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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