TY - JOUR
T1 - Healthy lifestyle behaviours and cardiovascular mortality among Japanese men and women
T2 - The Japan collaborative cohort study
AU - Eguchi, Eri
AU - Iso, Hiroyasu
AU - Tanabe, Naohito
AU - Wada, Yasuhiko
AU - Yatsuya, Hiroshi
AU - Kikuchi, Shogo
AU - Inaba, Yutaka
AU - Tamakoshi, Akiko
N1 - Funding Information:
This work was supported by grants-in-aid for scientific research from the Ministry of Education, Science, Sports and Culture of Japan (Monbusho); 61010076, 62010074, 63010074, 1010068, 2151065, 3151064, 4151063, 5151069, 6279102, 11181101, 17015022, 18014011, and 20014026.
Funding Information:
The authors sincerely express their appreciation to Dr Kunio Aoki, Professor Emeritus, Nagoya University School of Medicine and the former chairman of the JACC study, and Dr Haruo Sugano, the former Director, Cancer Institute, Tokyo, who greatly contributed to the initiation of the JACC study, as well as Dr Yoshiyuki Ohno, Professor Emeritus, Nagoya University School of Medicine, who was the past chairman of the study. The authors also wish to thank Dr Tomoyuki Kitagawa, Cancer Institute of the Japanese Foundation for Cancer Research and the former chairman of Grant-in-Aid for Scientific Research on Priority Area ‘Cancer’ and Dr Kazao Tajima, Aichi Cancer Center Research Institute and the former chairman of Grant-in Aid for Scientific Research on Priority Area of Cancer Epidemiology for their full support of this study.
PY - 2012/2
Y1 - 2012/2
N2 - Aims To examine the combined impacts of healthy lifestyle behaviours on cardiovascular disease (CVD) in Asians.Methods and resultsA total of 18 747 men and 24 263 women aged 4079 without a history of stroke or coronary heart disease (CHD) at baseline in 198890 were followed up until 2006. Participants scored one point for each following lifestyle behaviour: consumption of fruits <1 intake per day, fish <1 intake per day, milk almost every day, exercise <5 h per week and/or walking <1 h per day, body mass index (BMI) of 2125 kg/m 2, alcohol intake <46.0 g per day, non-smoking, and sleep duration of 5.57.5 h per day. During 16.5 years of follow-up, there were 1907 deaths from total CVDs including 849 strokes and 402 CHDs. For both genders, persons with the highest scores had the lowest CVD mortality. The multivariable hazard ratios (95 confidence interval, population-attributable fraction) for the highest (78) vs. lowest (02) score categories were 0.35 (0.250.49, 52.3) in men, and 0.24 (0.160.36, 44.6) in women. Similar associations were found for stroke: 0.36 (0.220.58, 45.0) in men and 0.28 (0.150.53, 43.4) in women, and for CHD: 0.19 (0.080.50, 76.2) and 0.20 (0.090.47, 34.5), respectively. ConclusionMortality from stroke, CHD, and CVD in the highest healthy lifestyle score category was one-third in men and one-fourth in women of those in the lowest scores, suggesting that a large fraction of CVD could be prevented through lifestyle modification.
AB - Aims To examine the combined impacts of healthy lifestyle behaviours on cardiovascular disease (CVD) in Asians.Methods and resultsA total of 18 747 men and 24 263 women aged 4079 without a history of stroke or coronary heart disease (CHD) at baseline in 198890 were followed up until 2006. Participants scored one point for each following lifestyle behaviour: consumption of fruits <1 intake per day, fish <1 intake per day, milk almost every day, exercise <5 h per week and/or walking <1 h per day, body mass index (BMI) of 2125 kg/m 2, alcohol intake <46.0 g per day, non-smoking, and sleep duration of 5.57.5 h per day. During 16.5 years of follow-up, there were 1907 deaths from total CVDs including 849 strokes and 402 CHDs. For both genders, persons with the highest scores had the lowest CVD mortality. The multivariable hazard ratios (95 confidence interval, population-attributable fraction) for the highest (78) vs. lowest (02) score categories were 0.35 (0.250.49, 52.3) in men, and 0.24 (0.160.36, 44.6) in women. Similar associations were found for stroke: 0.36 (0.220.58, 45.0) in men and 0.28 (0.150.53, 43.4) in women, and for CHD: 0.19 (0.080.50, 76.2) and 0.20 (0.090.47, 34.5), respectively. ConclusionMortality from stroke, CHD, and CVD in the highest healthy lifestyle score category was one-third in men and one-fourth in women of those in the lowest scores, suggesting that a large fraction of CVD could be prevented through lifestyle modification.
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U2 - 10.1093/eurheartj/ehr429
DO - 10.1093/eurheartj/ehr429
M3 - Article
C2 - 22334626
AN - SCOPUS:84857164987
SN - 0195-668X
VL - 33
SP - 467
EP - 477
JO - European heart journal
JF - European heart journal
IS - 4
ER -
