Hemolytic effect of surface roughness of an impeller in a centrifugal blood pump

Yoshiyuki Takami, Tadashi Nakazawa, Kenzo Makinouchi, Eiki Tayama, Julie Glueck, Robert Benkowski, Yukihiko Nosé

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15 Citations (Scopus)

Abstract

The present study investigates how the surface roughness of an impeller affects hemolysis in the pivot bearing supported Gyro C1E3 pump. This study focuses on particular areas of the impeller surface in the impeller type centrifugal pump. Seven Gyro C1E3 pumps were prepared with smooth surface housings and different impeller parts with different surface roughnesses. The vanes, top side, and backside of the impeller were independently subjected to vapor polishing, fine sand blasting, or coarse sand blasting to produce three different grades of surface roughness. These surfaces were then examined by surface profile instrument. Using these pumps with different impellers, in vitro hemolysis tests were performed simulating cardiopulmonary bypass (5 L/min, 350 mm Hg). The findings of this study conclusively proved that surface roughness of the back side of the impeller has the greatest effect on hemolysis followed by the top side and then the vanes. The following are reasons for these findings. First, the shear rate may be greater on the back side than on the top side because of the smaller gap between the back and the housing and the greater relative speed against the impeller. Second, the fluid beneath the impeller may have a longer exposure time because there is little chance for the fluid to mix beneath the impeller. Third, the shear rate may be greater on the top sid of the impeller than on the vanes because a vortex formulation occurs behind the vanes.

Original languageEnglish
Pages (from-to)686-690
Number of pages5
JournalArtificial Organs
Volume21
Issue number7
DOIs
Publication statusPublished - 01-01-1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

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  • Cite this

    Takami, Y., Nakazawa, T., Makinouchi, K., Tayama, E., Glueck, J., Benkowski, R., & Nosé, Y. (1997). Hemolytic effect of surface roughness of an impeller in a centrifugal blood pump. Artificial Organs, 21(7), 686-690. https://doi.org/10.1111/j.1525-1594.1997.tb03723.x