Hepatic arterial infusion chemotherapy (HAI) for advanced hepatocellular carcinoma inefficacious with transcatheter arterial embolization (TAE)

W. Takayama, T. Asano, S. Kobayashi, S. Nakagouri, T. Kenmochi, S. Okazumi, A. Takeda, T. Fukunaga, K. Iwasaki, K. Shutou, H. Matsuzaki, H. Aoyama, K. Shinotou, T. Kouno, K. Isono

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Abstract

For 6 patients with advanced hepatocellular carcinoma (HCC) in whom TAE was inefficacious, we tried hepatic arterial infusion chemotherapy. 5-FU 500 mg/day + CDDP 10 mg/day was administered during 5 days. The AFP level was decreased for 4 patients, and 2 patients showed a partial response in CT image. These 2 patients have been alive over 22 and 18 months, respectively. These results suggest that 5-FU + CDDP HAI might be a useful treatment of HCC inefficacious with TAE.

Original languageEnglish
Pages (from-to)867-871
Number of pages5
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume25
Issue number6
Publication statusPublished - 05-1998

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All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Takayama, W., Asano, T., Kobayashi, S., Nakagouri, S., Kenmochi, T., Okazumi, S., Takeda, A., Fukunaga, T., Iwasaki, K., Shutou, K., Matsuzaki, H., Aoyama, H., Shinotou, K., Kouno, T., & Isono, K. (1998). Hepatic arterial infusion chemotherapy (HAI) for advanced hepatocellular carcinoma inefficacious with transcatheter arterial embolization (TAE). Gan to kagaku ryoho. Cancer & chemotherapy, 25(6), 867-871.