HHV-6B and HHV-7 in Exanthema Subitum and Related Skin Diseases

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Primary human herpesvirus (HHV)-6B and HHV-7 infections can cause exanthem subitum, which is a common febrile exanthematous disease in childhood. Additionally, reactivation of the viruses has been implicated in skin manifestations. There are different incidence rates of exanthem subitum among patients with primary HHV-6B or HHV-7 infection in Japan and the United States. This disease is generally a benign, self-limiting disease, and it rarely causes complications such as febrile seizures and encephalitis. HHV-6B and HHV-7 reactivate in patients with drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptom (DRES), which has the clinical triad of fever, rash, and internal organ involvement due to drug exposure. Additionally, HHV-6B reactivation was associated with fever and skin rash or acute graft-versus-host disease in hematopoietic stem cell transplantation.

Original languageEnglish
Title of host publicationHuman Herpesviruses HHV-6A, HHV-6B, and HHV-7, Third Edition
PublisherElsevier B.V.
Pages153-166
Number of pages14
ISBN (Print)9780444627032
DOIs
Publication statusPublished - 01-01-2014

Fingerprint

Exanthema Subitum
Human Herpesvirus 7
Human Herpesvirus 6
Exanthema
Skin Diseases
Drug Hypersensitivity Syndrome
Herpesviridae Infections
Fever
Skin Manifestations
Febrile Seizures
Hematopoietic Stem Cell Transplantation
Graft vs Host Disease
Encephalitis
Japan
Viruses
Incidence
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Immunology and Microbiology(all)

Cite this

Yoshikawa, T. (2014). HHV-6B and HHV-7 in Exanthema Subitum and Related Skin Diseases. In Human Herpesviruses HHV-6A, HHV-6B, and HHV-7, Third Edition (pp. 153-166). Elsevier B.V.. https://doi.org/10.1016/B978-0-444-62703-2.00009-4
Yoshikawa, Tetsushi. / HHV-6B and HHV-7 in Exanthema Subitum and Related Skin Diseases. Human Herpesviruses HHV-6A, HHV-6B, and HHV-7, Third Edition. Elsevier B.V., 2014. pp. 153-166
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Yoshikawa, T 2014, HHV-6B and HHV-7 in Exanthema Subitum and Related Skin Diseases. in Human Herpesviruses HHV-6A, HHV-6B, and HHV-7, Third Edition. Elsevier B.V., pp. 153-166. https://doi.org/10.1016/B978-0-444-62703-2.00009-4

HHV-6B and HHV-7 in Exanthema Subitum and Related Skin Diseases. / Yoshikawa, Tetsushi.

Human Herpesviruses HHV-6A, HHV-6B, and HHV-7, Third Edition. Elsevier B.V., 2014. p. 153-166.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Yoshikawa T. HHV-6B and HHV-7 in Exanthema Subitum and Related Skin Diseases. In Human Herpesviruses HHV-6A, HHV-6B, and HHV-7, Third Edition. Elsevier B.V. 2014. p. 153-166 https://doi.org/10.1016/B978-0-444-62703-2.00009-4