High dose external radiotherapy (≫50Gy) for loco-regional recurrence of rectal cancer after initial radical surgery

S. Hayashi, N. Ohashi, H. Hoshi, T. Iida, K. Sugisaki, H. Miyake, S. Kawaguchi

Research output: Contribution to journalArticle

Abstract

Thirty-one patients with loco-regional recurrence of rectal cancer were treated with high dose (≫50Gy) external radiotherapy during the period from 1994 to 2000. We analyzed the treatment outcomes, prognostic factors for local control, relief of symptoms and complications. Multivariate analysis was applied to identify possible prognostic factors for local control. Pattern of pelvic local recurrence was the only variable that significantly influenced local control. Six patients (19%) developed grade 3-4 late morbidity. In conclusion, high dose external radiotherapy (≫50Gy) was effective for the localized pattern of recurrence. The optimal high dose radiotherapy should be explored for patients with the localized recurrence.

Original languageEnglish
Pages (from-to)307-312
Number of pages6
JournalJapanese Journal of Clinical Radiology
Volume47
Issue number2
Publication statusPublished - 2002

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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