High-fructose consumption and the epigenetics of DNA methylation

Hiroya Yamada, Eiji Munetsuna, Koji Ohashi

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


Epidemiological studies have been demonstrated that fructose, which are used for beverages, are associated with the incidence of metabolic disorders. However, the pathological mechanism of fructose effect remains unclear. Recently, there are accumulating evidences that nutrition status may induce epigenetic modification, which lead to cause several diseases such as diabetes. Interestingly, it is becoming clear that the adverse effect of fructose is mediated by epigenetic modifications. Here, this chapter describes the epigenetic effect of high-fructose consumption.

Original languageEnglish
Title of host publicationHandbook of Nutrition, Diet, and Epigenetics
PublisherSpringer International Publishing
Number of pages17
ISBN (Electronic)9783319555300
ISBN (Print)9783319555294
Publication statusPublished - 05-01-2019

All Science Journal Classification (ASJC) codes

  • General Medicine
  • General Biochemistry,Genetics and Molecular Biology


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