High prevalence of metallo-β-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil

Yohei Doi, Angela C.R. Ghilardi, Jennifer Adams, Doroti De Oliveira Garcia, David L. Paterson

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Rates of metallo-β-lactamase and 16S rRNA methylase production were investigated in 51 imipenem-resistant Pseudomonas aeruginosa clinical isolates collected from hospitals in São Paulo, Brazil. Of them, 57% and 75% produced SPM-1 and RmtD, respectively. Of note, 51% produced both enzymes, suggesting that their coproduction is already common in this geographic area.

Original languageEnglish
Pages (from-to)3388-3390
Number of pages3
JournalAntimicrobial agents and chemotherapy
Issue number9
Publication statusPublished - 01-09-2007


All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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