High prevalence of metallo-β-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil

Yohei Doi, Angela C.R. Ghilardi, Jennifer Adams, Doroti De Oliveira Garcia, David L. Paterson

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Rates of metallo-β-lactamase and 16S rRNA methylase production were investigated in 51 imipenem-resistant Pseudomonas aeruginosa clinical isolates collected from hospitals in São Paulo, Brazil. Of them, 57% and 75% produced SPM-1 and RmtD, respectively. Of note, 51% produced both enzymes, suggesting that their coproduction is already common in this geographic area.

Original languageEnglish
Pages (from-to)3388-3390
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume51
Issue number9
DOIs
Publication statusPublished - 01-09-2007

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Imipenem
Pseudomonas aeruginosa
Brazil
Enzymes
rRNA (adenosine-O-2'-)methyltransferase

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Doi, Yohei ; Ghilardi, Angela C.R. ; Adams, Jennifer ; De Oliveira Garcia, Doroti ; Paterson, David L. / High prevalence of metallo-β-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil. In: Antimicrobial agents and chemotherapy. 2007 ; Vol. 51, No. 9. pp. 3388-3390.
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High prevalence of metallo-β-lactamase and 16S rRNA methylase coproduction among imipenem-resistant Pseudomonas aeruginosa isolates in Brazil. / Doi, Yohei; Ghilardi, Angela C.R.; Adams, Jennifer; De Oliveira Garcia, Doroti; Paterson, David L.

In: Antimicrobial agents and chemotherapy, Vol. 51, No. 9, 01.09.2007, p. 3388-3390.

Research output: Contribution to journalArticle

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