Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes

Tsuneo Masui, Hayao Nakanishi, Ken Ichi Inada, Toshio Imai, Yasumoto Mizoguchi, Hideaki Yada, Mitsuru Futakuchi, Tomoyuki Shirai, Masae Tatematsu

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Medicine & Life Sciences